Results 211 to 220 of about 3,856,896 (414)

Provision of naloxone to injection drug users as an overdose prevention strategy: Early evidence from a pilot study in New York City [PDF]

open access: green, 2005
Sandro Galea   +5 more
openalex   +1 more source

Changes in Protein Expression of Renal Drug Transporters and Drug‐Metabolizing Enzymes in Autosomal Dominant Polycystic Kidney Disease Patients

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Autosomal dominant polycystic kidney disease is the most prevalent inherited kidney disease and leads to bilateral kidney enlargement and progressive loss of renal function, often over decades. Comorbidities include hypertension, flank pain, and bacterial infections. The condition often necessitates prolonged multidrug therapy.
Annika C. Tillmann   +6 more
wiley   +1 more source

Drug overdose deaths in 28 states and the District of Columbia : 2020 data from the State Unintentional Drug Overdose Reporting System [PDF]

open access: yes
Key findings:\u2022 In 2020, 38,048 drug overdose deaths were reported from 28 states and DC for an age-adjusted rate of 30.6 per 100,000 people\u2022 70% of drug overdose deaths involved illicitly manufactured fentanyls (IMFs)\u2022 The rate of drug ...

core  

Rapid Analytical Method for Quantification of Gamma‐Hydroxybutyrate (GHB) in Hair by UPLC‐MS/MS

open access: yesDrug Testing and Analysis, EarlyView.
A rapid and simple UPLC‐MS/MS method for quantification of GHB in 10 mg of hair was developed. The method was satisfactorily validated, showing a linear range of 0.5–50 ng/mg, which allows us to quantify endogenous and exogenous GHB concentrations.
Miriam Blanco‐Ces   +5 more
wiley   +1 more source

Retrospective Evaluation of Novel Synthetic Opioids and Xylazine Chronic Intake by Post‐Mortem Hair Testing

open access: yesDrug Testing and Analysis, EarlyView.
The study presents a validated UPLC‐MS/MS method applied for the detection of fentanyl, NPFs, xylazine, nitazenes in hair samples from 250 post‐mortem cases collected at the Jefferson County Coroner/Medical Examiner's Office (Birmingham, AL, USA). In 52% of the analyzed hair samples, fentanyl, its main metabolites, and related analogs were detected ...
Marco Ballotari   +6 more
wiley   +1 more source

Predictors of accidental fatal drug overdose among a cohort of injection drug users

open access: green, 2001
P. T. O’Driscoll   +5 more
openalex   +1 more source

Comprehensive Qualitative Drug Screening in Emergency Toxicology Using an Automated LC–MSn System:Simultaneous Quantification of Relevant Drugs and Metabolites in Blood Plasma

open access: yesDrug Testing and Analysis, EarlyView.
Simultaneous qualitative and quantitative analysis of 62 drugs and seven active metabolites in human blood plasma by automated liquid chromatography linear ion trap mass spectrometry. ABSTRACT Rapid and comprehensive qualitative and quantitative analytical procedures are crucial in 24/7 emergency toxicology (ET) to support diagnosis and treatment of ...
Selina Hemmer   +4 more
wiley   +1 more source

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