Results 111 to 120 of about 2,091,574 (290)

Brief strategic family therapy for adolescent drug abuse. [PDF]

, 2003
To ensure that treatment providers apply the most current scientifically supported approaches to their patients, NIDA has supported the development of the "Therapy Manuals for Drug Addiction" series.

core  

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Phytosanitary Regulation for Packaging (ISPM-15)

, 2018
International Standards for Phytosanitary Measures No. 15 (ISPM 15) is essential for the regulation of wooden pallet and packaging materials. This regulation measure is important in determining how pallet industries and professionals need to handle ...
Treaster, Garrett
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Technology in the packaging of the future

, 2022
reservedCon il termine packaging si tende ad indicare solo un componente dei prodotti che troviamo sul mercato, un componente che nella maggior parte dei casi si tende a considerare poco importante o secondario.
CORSI, RICCARDO
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Multi-homosubunit dsRNA/dsDNA virus genome packaging nanomotors with sequential revolving mechanisms for potent drug development

Frontiers in RNA Research
The emergence of new viral diseases and viral drug resistance presents a critical challenge in human health. Recent structural and mechanistic studies have revealed remarkable parallels and structural similarities among viral dsDNA- and dsRNA-packaging ...
Margaret Bohmer, Margaret Bohmer, Margaret Bohmer, Margaret Bohmer, Margaret Bohmer, Justin Gnarra, Daniel W. Binzel, Daniel W. Binzel, Daniel W. Binzel, Daniel W. Binzel, Daniel W. Binzel, Tao Weitao, Peixuan Guo, Peixuan Guo, Peixuan Guo, Peixuan Guo, Peixuan Guo   +16 more
doaj   +1 more source

Finding Aid for UW-Stout Packaging Program, 1964-1990

, 1964
Black and white and color photographs of UW-Stout Packaging Program and Packaging Lab equipment, classes, committees, student groups, banquets, Packaging Department, Packaging Program booklet (laminated photographs), and photographs mounted to foam core ...
UW-Stout Packaging Department
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source