Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Impact of Variation in Pill/Package Appearance of Drugs on Patients’ Behavior: A Systematic Review
, 2021 Blanca Lumbreras +2 more
openalex +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Consumer Perceptions of Organic, Natural, and Conventional Products When Provided at the Same Price. [PDF]
, 2019 Today’s grocery stores are filled aisle to aisle with an overwhelming variety of options for the consumer. In a consumer-driven market structure, the food industry has grown to encompass many niche markets which meet the ever changing demands of ...
Sigmon, Kylee
core +2 more sources
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Human health benefit and burden of the schizophrenia health care pathway in Belgium : paliperidone palmitate long-acting injections [PDF]
, 2019 De Smedt, Delphine +4 more
core +1 more source
Warnings and Disclosures [PDF]
, 2011 This chapter reviews nearly six decades of research on warnings and disclosures, including common misperceptions and their importance to public health policy, and offers an answer to the key question, “Do warnings and disclosures really work?” Supporting
Andrews, J. Craig
core +1 more source
Netpredictor: R and Shiny package to perform Drug-Target Bipartite network analysis and prediction of missing links [PDF]
, 2016 Abhik Seal, David Wild
openalex +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Markovian negentropies in bioinformatics. 1. A picture of footprints after the interaction of the HIV-1 Ψ-RNA packaging region with drugs [PDF]
, 2003 Humberto González‐Díaz +2 more
openalex +1 more source