Results 221 to 230 of about 4,880,703 (380)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Promising measures for minimising e-cigarette youth uptake in countries with a significant e-cigarette market. [PDF]

Lancet Reg Health Eur
Hiscock R.
europepmc   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Package of interventions for harm reduction among women who inject drugs in Nigeria [PDF]

Aisha Dadi, Olujide Arije, Kene Eruchalu, Jennifer Anyanti, Omokhudu Idogho, Yamen Okonkwo, Patrick Ikani   +6 more
openalex   +1 more source

EFFECTIVENESS OF INFORMATION, EDUCATION AND COMMUNICATION (IEC) PACKAGE ON KNOWLEDGE AND ATTITUDE REGARDING OVER THE COUNTER (OTC) DRUGS AMONG ADULTS

, 2020
R Jayalakshmi, S. Ani Grace Kalaimathi
openalex   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Applications of Chitosan, an Eco-Friendly Biopolymer in Agricultural Systems, Herbal Products, and Functional Foods: A Review. [PDF]

Food Sci Nutr
Karimlar S, Pirbalouti AG, Teymuori Z, Moslehishad M, Hamidi-Esfahani Z.   +4 more
europepmc   +1 more source

FDA Regulation of Electronic Nicotine Delivery Systems and the “Deeming” Rule: What’s Left for States? [PDF]

, 2018
Hoke, Kathleen, Sager, Mellissa, Tilburg, William   +2 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Understanding the Impact of Sustainable Pharmaceutical Packaging on the Chemical Stability of Silodosin. [PDF]

Pharmaceutics
Visa C, Rodriguez R, Rincón Á, Peña S, Serrano DR, Torrado JJ.   +5 more
europepmc   +1 more source