Results 91 to 100 of about 1,920,311 (233)

Self-medication: A Harmful Practice and a Cause of Poisoning Admissions in a Tertiary Care Hospital in Eastern India [PDF]

open access: yesBengal Physician Journal
Background: The pattern of poisoning in India varies with socioeconomic status as well as region. A thorough understanding of the demographics and management of poisoning cases is essential for the development of well-informed policies, targeted ...
Tanmoy Biswas   +3 more
doaj   +1 more source

SELF-POISONING SUICIDE ATTEMPTS AMONG STUDENTS IN TEHRAN, IRAN [PDF]

open access: yes
Background: This study aim was to describe the epidemiology of intentional self-poisoning among students. Subjects and methods: A cross-sectional study was conducted on self-poisoned students admitted to Loghman-Hakim Hospital in Tehran, Iran. Variables
Alfred, Sam   +5 more
core  

Structural Basis of Shiga Toxin Neutralization by Human Antibodies Targeting Canonical Receptor‐Binding and Non‐Canonical Assembly Sites

open access: yesAdvanced Science, EarlyView.
Cryo‐electron microscopy structures reveal two distinct neutralization mechanisms of fully human monoclonal antibodies targeting the Shiga toxin 1a B subunit. RDS059 occludes the Gb3 receptor‐binding site, whereas RDS045 engages a lateral quaternary epitope to disrupt holotoxin assembly.
Jianting Ke   +10 more
wiley   +1 more source

Complete Pathway Refactoring and Combinatorial Biosynthesis of Anthracyclines for Modulation of Histone Eviction and DNA Damage Bioactivities

open access: yesAngewandte Chemie, EarlyView.
A synthetic biology platform was established for the complete refactoring of complex anthracycline biosynthetic pathways in Streptomyces coelicolor using standardized, chemically synthetic DNA parts. This modular construction enabled streamlined combinatorial biosynthesis, yielding novel analogs that decouple DNA damage from chromatin damage (histone ...
Rongbin Wang   +15 more
wiley   +2 more sources

Self‐Propelled HPB@Lip@AB Nanomotors Ameliorate Dry Eye Disease

open access: yesAdvanced Science, EarlyView.
A self‐propelled HPB@Lip@AB nanomotor system is developed for dry eye disease (DED) therapy, facilitating rapid penetration across ocular surface barriers while integrating hydrogen therapy with multi‐enzyme‐like antioxidant activity. The nanoplatform restores mitochondrial function, suppresses oxidative stress, inflammation, and apoptosis, and ...
Jing Li   +9 more
wiley   +1 more source

Other title: Drug Poisoning Deaths, 2000-2017

open access: yes, 2018
"In 2017, non-heroin opioid drugs or substances continued to remain a persistent contributing cause of at least 1 out of 3 drug poisoning deaths. Other drugs contributing to drug poisoning deaths include psychostimulants, benzodiazepines, and heroin."; "
Kansas. Department of Health and Environment.
core   +1 more source

Heterobimetallic Janus Catalysts for the One‐Pot Synthesis of Polar‐Apolar Block Copolymers

open access: yesAngewandte Chemie, EarlyView.
Heterobimetallic Janus catalysts act as bifunctional initiators, combining two distinct polymerisation mechanisms in one pot to deliver well‐defined apolar‐polar block copolymers. Combining Earth abundant Ti and Al catalysts for respective α‐olefin and lactone polymerisation, the orthogonal activity is enabled by unprecedented initiation from a Ti ...
Raju Chambenahalli   +2 more
wiley   +2 more sources

Drug Poisonings among Patients Presenting to the Emergency Department of a Tertiary Care Center in Eastern Nepal: An Observational Study

open access: yesJournal of Nepal Medical Association
Introduction: Drug poisoning is a major public health concern contributing to emergency visits and hospital admissions. Understanding the patterns and characteristics of drug poisoning cases is crucial for developing targeted prevention strategies ...
Namita Kumari Mandal   +3 more
doaj   +1 more source

Trends in drug-poisoning deaths involving opioid analgesics and heroin : United States, 1999\u20132012 [PDF]

open access: yes
This Health E-Stat provides information on annual rates of all drug-poisoning deaths and drug-poisoning deaths involving opioid analgesics and heroin for 1999 through 2012 using data from the Centers for Disease Control and Prevention's (CDC) National ...

core  

The Familial Factors and Demographic Characteristics of Children with Drug Poisoning

open access: yes, 2013
Aim: The purpose of this study was to investigate the demographic characteristics, role of family factors, etiology and the factors affecting the prognosis in children who had been admitted to our hospital between 04 August 2007 and 24 January 2009 due ...
Mahmut Çivilibal   +4 more
core   +1 more source

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