Results 121 to 130 of about 7,344,621 (307)
Drug Science and British Drug Policy: Critical Analysis of the Misuse of Drugs Act 1971
For half a century the Misuse of Drugs Act 1971 has dominated ill-conceived approaches to the prohibition of drugs and the criminalisation of many offenders.
Crome, Illana, Stevens, Alex, Nutt, D.
core
Tumor‐associated inflammation retains antibody‐targeted or non‐specific antibody conjugated nanoparticles within the tumor microenvironment. Magnetic Particle Imaging (MPI) enables non‐invasive detection and differentiation of tumors from other organs, owing to higher nanoparticle retention by inflammatory cells in the tumor periphery.
Preethi Korangath +9 more
wiley +1 more source
Drug policy and women: addressing the negative consequences of harmful drug control. [PDF]
A number of reports have documented the negative consequences of current prohibitionist drug control policies on health, human rights and development,1 and these are the subject of growing international attention.2 The past thirty years has also seen a ...
Birgin, Ruth +3 more
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Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu +5 more
wiley +1 more source
A sono‐responsive chemo‐immune checkpoint nanoinhibitor (Sono‐TT8) co‐delivering TPZ chemotherapy and siXkr8 simultaneously kills tumor cells and blocks PS externalization, reversing chemotherapy‐induced immunosuppression and enhancing antitumor immunity. ABSTRACT Breast cancer features an immunosuppressive tumor microenvironment following chemotherapy
Yunfan Liu +13 more
wiley +1 more source
This study systematically assessed the global burden and temporal trends of EOTBL cancer in individuals aged 15–49 years. Smoking, ambient particulate matter pollution, and secondhand smoke remain dominant risk factors. Countries within the same Human Development Index (HDI) category exhibit distinct epidemiological trajectories, underscoring the need ...
Ye Tian +8 more
wiley +1 more source
Why are the police against drug policy liberalisation? [PDF]
Johnstad PG.
europepmc +1 more source
Smart Bioinks for 4D Bioprinting: Requirements, Design, and Applications
Smart bioinks empower 4D‐bioprinted constructs to dynamically adapt and remodel in response to stimuli, effectively biomimicking native tissues. Artificial Intelligence (AI) and Machine Learning (ML) play a guiding role in their rational design by optimizing relevant properties.
Shangsi Chen +11 more
wiley +1 more source
Alternate‐day fasting suppresses mitochondrial complex II assembly via SDHAF4 to upregulate hepatocyte eNOS. The resulting nitric oxide S‐nitrosylates ATG7 at C184 in hepatic stellate cells, restraining autophagic flux and preventing their profibrotic activation.
Xueqiang Wang +17 more
wiley +1 more source
How academics and service providers are working together to inform drug policy in Ireland.
Since 2015, the LSE’s International Drug Policy Unit has been working with local partners the Ana Liffey Drug Project to help foster a new era of progressive drug policies in Ireland.
Duffin, Tony
core

