Advanced Experiment Design Strategies for Drug Development
Wang et al. analyze 592 drug development studies published between 2020 and 2024 that applied design of experiments methodologies. The review surveys both classical and emerging approaches—including Bayesian optimization and active learning—and identifies a critical gap between advanced experimental strategies and their practical adoption in ...
Fanjin Wang +3 more
wiley +1 more source
A sex-sensitive LC-MS/MS method with isotopic internal standard for prazosin bioequivalence: bridging precision medicine and generic drug policy in China. [PDF]
Chen H, Guo J, Zhu Z, Huang X, Guo J.
europepmc +1 more source
This perspective highlights how knowledge‐guided artificial intelligence can address key challenges in manufacturing inverse design, including high‐dimensional search spaces, limited data, and process constraints. It focused on three complementary pillars—expert‐guided problem definition, physics‐informed machine learning, and large language model ...
Hugon Lee +3 more
wiley +1 more source
[Impact of an integrated and centralized drug policy: the case of the province of Buenos Aires, ArgentinaImpacto de uma política de medicamentos integrada e centralizada: o caso da província de Buenos Aires, Argentina]. [PDF]
Marín GH +7 more
europepmc +1 more source
Understanding the Impacts of Novel Coronavirus Outbreaks on People Who Use Drugs: A Systematic Review to Inform Practice and Drug Policy Responses to COVID-19. [PDF]
Munro A +6 more
europepmc +1 more source
Evolution of Physical Intelligence Across Scales
By following the evolution of physical intelligence across scales, this article shows how intelligence arises from materials, structures, physical interactions, and collectives. It establishes physical intelligence as the evolutionary foundation upon which embodied intelligence is built.
Ke Liu +7 more
wiley +1 more source
Unpacking the process of developing South Africa's national drug policy - lessons for universal health coverage. [PDF]
Gray AL, Suleman F.
europepmc +1 more source
Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova +4 more
wiley +1 more source
“There’s many a slip between cup and lip” …. As there is between package and sale
Claire Wilkinson
doaj +1 more source
"Everyone says 'safe sex' but no one ever says 'safe drugs', you know?": Perspectives on the intersection of drug checking services, drug policy and the overdose crisis. [PDF]
Ondocsin J +6 more
europepmc +1 more source

