Results 91 to 100 of about 4,307,548 (391)
Profile of drug interactions in hospitalized children
Introduction: The expected therapeutic response may be affected by the presence of drug interactions. With the high number of reports on new drug interactions, it has been difficult for health professionals to keep constantly updated.
Martinbiancho J +3 more
doaj
Off-label and unlicensed drug use in a Spanish Neonatal Intensive Care Unit
Objetive: To describe off-label and unlicensed drugs in clinical practice in a Neonatal Intensive Care Unit (NICU).Method: The design of the study was a descriptive and retrospective three months research in a NICU of a Spanish University Hospital.
Belén Cabezuelo Escribano +6 more
doaj +1 more source
Objective In complex diseases, it is challenging to assess a patient's disease state, trajectory, treatment exposures, and risk of multiple outcomes simultaneously, efficiently, and at the point of care. Methods We developed an interactive patient‐level data visualization and analysis tool (VAT) that automates illustration of the trajectory of a ...
Ji Soo Kim +18 more
wiley +1 more source
Drug–Drug Interactions in COPD Therapy: A Community Pharmacy Study
Background: [...]
Maria-Medana Drăgoi +2 more
doaj +1 more source
Automated Detection of Systematic Off-label Drug Use in Free Text of Electronic Medical Records. [PDF]
Off-label use of a drug occurs when it is used in a manner that deviates from its FDA label. Studies estimate that 21% of prescriptions are off-label, with only 27% of those uses supported by evidence of safety and efficacy.
Jung, Kenneth +2 more
core +2 more sources
Hydroxychloroquine Associated With Lower Glomerular Filtration Rate Decline in Lupus Nephritis
Objective Hydroxychloroquine (HCQ) protects kidney function in lupus nephritis (LN) by preventing flares, yet some cohort studies show no significant benefit in kidney function with HCQ. Clarifying these conflicting findings by showing early and long‐term benefits of HCQ on kidney function preservation is critical.
Shivani Garg +9 more
wiley +1 more source
Background Inappropriate prescribing has been estimated to be as high as 40% in long-term care. The purpose of this study was to develop a computer program that identifies potentially inappropriate drug prescriptions and to test its reliability.
Ferko Nicole +6 more
doaj +1 more source
Long‐Term Opioids in Gout: A Matched Cohort Study From the Veterans Health Administration
Objective Though used frequently to treat flare, risk of long‐term opioid exposure in gout has not been well defined. In this study, we examined the hypothesis that people with gout are more likely than individuals without gout to be prescribed long‐term opioids over time.
Lindsay N. Helget +7 more
wiley +1 more source
OBJECTIVES: The aim of this study was to develop a strategy to identify adverse drug events associated with drug-drug interactions by analyzing the prescriptions of critically ill patients.
Grazielle Viana Ramos +3 more
doaj +1 more source
Implications of the problem orientated medical record (POMR) for research using electronic GP databases: a comparison of the Doctors Independent Network Database (DIN) and the General Practice Research Database (GPRD). [PDF]
Background The General Practice Research Database (GPRD) and Doctor's Independent Network Database (DIN), are large electronic primary care databases compiled in the UK during the 1990s.
David P Strachan +15 more
core +3 more sources

