Results 81 to 90 of about 137,573 (297)

Immune Checkpoint Inhibitor–Related Myositis and Associated Triad Overlap Syndrome

Arthritis Care &Research, EarlyView.
Objective Immune checkpoint inhibitor (ICI) myositis is a rare but a highly morbid condition, particularly with the ICI myositis triad syndrome of myositis, myocarditis, and myasthenia gravis. We report the clinical characteristics of ICI myositis and all‐cause mortality in these patients.
Selene Rubino, Grant W. Cannon, Brian C. Sauer, Jorge Rojas, Gregory J. Stoddard, Gary A. Kunkel, Jessica A. Walsh, Bryant R. England, Joshua F. Baker, Tawnie J. Braaten   +9 more
wiley   +1 more source

Effect of Implementing a Dashboard With or Without a Best Practice Alert on HLA‐B*58:01 Testing Rates Among Allopurinol Users at VA Medical Centers

Arthritis Care &Research, EarlyView.
Objective The American College of Rheumatology recommends HLA‐B*58:01 allele testing before the initiation of allopurinol, specifically among Asian and African American/Black patients, due to their increased risk for severe hypersensitivity reactions. However, testing rates remain low at many health care facilities.
Abimbola Fadairo‐Azinge, Gabriela Schmajuk, Sristi Sharma, Colleen P. Flanagan, Sara Faghihi‐Kashani, Ning Zhang, Mary A. Whooley   +6 more
wiley   +1 more source

Study highlights long-term prescription drug use. [PDF]

, 2018
One-third of medical card patients receive long-term prescriptions for drugs that can lose their effect and cause problems such as falls, according to the first detailed analysis of benzodiazepine and Z-drug prescribing in Ireland.....
Shanahan, Catherine
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Paediatric drug use with focus on off-label prescriptions in Lombardy and implications for therapeutic approaches [PDF]

, 2013
The persistent lack of information on the paediatric use of most medicinal products is a major hindrance towards an optimal treatment of paediatric patients.
S. Antoniazzi, M. Venegoni, M. Pozzi, C. Carnovale, E. Clementi, S. Radice, L. Merlino, V. Perrone, V. Conti   +8 more
core   +1 more source

Drug prescription before and after implementation of a CPOE system on the Paediatric Intensive Care Unit: a quality improvement study

Swiss Medical Weekly
STUDY AIMS: Paediatric drug prescription is complex, especially in the paediatric intensive care unit (PICU), where errors may be particularly harmful due to frequent use of high-risk medications.
Rebecca Angresius, Katharina Wyss, Diana Reppucci , Florian Rebling , Ulrike Subotic , Verena Gotta   +5 more
doaj   +1 more source

Clinical risk management in Dutch community pharmacies: the case of drug-drug interactions. [PDF]

, 2006
Item does not contain fulltextBACKGROUND: The prevention of drug-drug interactions requires a systematic approach for which the concept of clinical risk management can be used.
Dep Farmaceutische wetenschappen, Smet, P.A.G.M. de, Population-based studies of drug treatment: from molecule to patient outcomes, Egberts, A.C.G., de Smet, P.G.A.M., Buurma, H.   +5 more
core   +1 more source

Paediatric off-label use of drugs in Gansu, China: a multicentre cross-sectional study

BMJ Open
Objective To examine the current prevalence and cost of paediatric off-label drug prescriptions in Gansu, China, and the potential influencing factors.Design The prevalence of off-label prescriptions in paediatrics was evaluated according to the National
Xufei Luo, Yaolong Chen, Yang Gao, Qiu Li, Yan Yang, Min Tian, Min Meng, Bin Ge, Wenjuan Lei, Yuqiong Wu, Yali Lu, Tingji Shao, Jiawei Luo   +12 more
doaj   +1 more source

Preventable adverse drug events in critically ill HIV patients: Is the detection of potential drug-drug interactions a useful tool?

Clinics, 2018
OBJECTIVES: The aim of this study was to develop a strategy to identify adverse drug events associated with drug-drug interactions by analyzing the prescriptions of critically ill patients.
Grazielle Viana Ramos, André Miguel Japiassú, Fernando Augusto Bozza, Lusiele Guaraldo   +3 more
doaj   +1 more source

Risk of Retinopathy Associated with Long‐Term Use of Hydroxychloroquine in Patients with Rheumatic Diseases: A Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective We aimed to estimate the prevalence and cumulative incidence of hydroxychloroquine retinopathy (HCQ‐R) and its risk factors among patients receiving long‐term HCQ with rheumatic diseases through a systematic review and meta‐analysis of observational studies that used spectral‐domain optical coherence tomography (SD‐OCT) for screening ...
Narsis Daftarian, Chloe Yue, Steve D Levasseur, Hui Xie, J. Antonio Avina‐Zubieta   +4 more
wiley   +1 more source

Stagnation in the Drug Development Process: Are Patents the Problem? [PDF]

The rate of new drug development has stagnated, in spite of large increases in both private and public sector spending on biomedical research. The flip side of slower progress is higher drug costs.
Dean Baker
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