Results 61 to 70 of about 6,763,509 (345)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Correction for potentially inappropriate prescribing can increase specificity when using drug prescriptions as an adjunct to diagnostic codes to assess comorbidities in older patients

Epidemiology, Biostatistics and Public Health, 2022
Background: Comorbidities are a growing problem in older patients in many clinical settings, but electronic records may give an unsatisfactory picture of this complexity.
Gianfrancesco Fiorini, Alberto Castagna, Cesare Cerri, Vincenzo Rega, Antonello E. Rigamonti, Silvano G. Cella   +5 more
doaj  

Benzodiazepine, z-drug and pregabalin prescriptions and mortality among patients in opioid maintenance treatment-A nation-wide register-based open cohort study.

Drug and Alcohol Dependence, 2017
BACKGROUND Use of sedatives may increase risk of death in opioid users. The aim of the study was to assess whether prescription of sedatives may be associated with mortality in patients in opioid maintenance treatment.
T. Abrahamsson, Jonas Berge, A. Öjehagen, A. Håkansson   +3 more
semanticscholar   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Effect of Prescription Drug Coverage on the Elderly's Use of Prescription Drugs

INQUIRY: The Journal of Health Care Organization, Provision, and Financing, 2009
This paper evaluates the effect of prescription drug insurance coverage on prescription drug use among the elderly. Estimates were obtained using multivariate regression and a fixed-effects (within-person) research design that controls for unmeasured person-specific effects that may confound the relationships of interest.
Nasreen Khan, Robert Kaestner
openaire   +3 more sources

Prescription Drug Monitoring and Dispensing of Prescription Opioids [PDF]

Public Health Reports®, 2014
Objective. In the United States, per-capita opioid dispensing has increased concurrently with analgesic-related mortality and morbidity since the 1990s. To deter diversion and abuse of controlled substances, most states have implemented electronic prescription drug monitoring programs (PDMPs).
Joanne E, Brady, Hannah, Wunsch, Charles, DiMaggio, Barbara H, Lang, James, Giglio, Guohua, Li   +5 more
openaire   +2 more sources

Potential intravenous drug interactions in intensive care

Revista da Escola de Enfermagem da USP
OBJECTIVE To analyze potential intravenous drug interactions, and their level of severity associated with the administration of these drugs based on the prescriptions of an intensive care unit.
Maiara Benevides Moreira, Maria Gefé da Rosa Mesquita, Marluci Andrade Conceição Stipp, Graciele Oroski Paes   +3 more
doaj   +1 more source

Racial-Ethnic Disparities in Opioid Prescriptions at Emergency Department Visits for Conditions Commonly Associated with Prescription Drug Abuse

PLoS ONE, 2016
Prescription drug abuse is a growing problem nationally. In an effort to curb this problem, emergency physicians might rely on subjective cues such as race-ethnicity, often unknowingly, when prescribing opioids for pain-related complaints, especially for
A. Singhal, Yu-Yu Tien, R. Hsia
semanticscholar   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

The Origin of Compulsory Drug Prescriptions [PDF]

The Journal of Law and Economics, 1979
BEFORE 1938, the only drugs for which prescriptions were needed were certain narcotics specified in the Harrison Anti-Narcotics Act of 1914.1 Any other drug could be obtained by walking into a pharmacy and buying it. If a person wished to see a doctor and get a prescription, he could. But any nonnarcotic drug he could buy with a prescription could also
openaire   +3 more sources