Sox6 expression is elevated in hypertensive conditions and promotes vascular smooth muscle cell phenotypic switching through autophagy activation. Using gain‐ and loss‐of‐function approaches both in vitro and in vivo, we demonstrate that Sox6 regulates blood pressure and vascular remodeling, highlighting its potential as a novel therapeutic target for ...
Qianhui Ling+7 more
wiley +1 more source
Costs are a major driver of antibacterial drug prescriptions in Germany: market analysis from 1985 to 2022. [PDF]
Bindel LJ, Seifert R.
europepmc +1 more source
Objective To compare clinical and radiological outcomes among relapsing multiple sclerosis patients treated with autologous hematopoietic stem cell transplantation (AHSCT), alemtuzumab (ATZ), and ocrelizumab (OCR). Methods From a London (UK) hospital‐based observational cohort, modeled data were obtained from 621 relapsing–remitting multiple sclerosis ...
Paolo Antonio Muraro+16 more
wiley +1 more source
Daily defined dose-costs have a stronger influence on antibacterial drug prescriptions in Germany than bacterial resistance: economic factors are more important than scientific evidence. [PDF]
Bindel LJ, Seifert R.
europepmc +1 more source
A Network Approach for the Study of Drug Prescriptions: Analysis of Administrative Records from a Local Health Unit (ASL TO4, Regione Piemonte, Italy). [PDF]
Miglio G+10 more
europepmc +1 more source
Clinton to regulate internet prescription drug sales [PDF]
F. Charatan
openalex +1 more source
Luspatercept in Transfusion‐Dependent β‐Thalassemia: The Benefit Is Real, and So Are the Risks
American Journal of Hematology, EarlyView.
Khaled M. Musallam
wiley +1 more source
Cholinergic Degeneration and Cognitive Function in Early GBA1‐Related Parkinson's Disease
Objective The phenotype of patients with Parkinson's disease carrying GBA1 variants (GBA‐PD) suggest similarities to symptomatology associated with early cholinergic system degeneration. Therefore, this study aims to investigate the clinical features and the cholinergic innervation pattern in patients with early GBA‐PD versus those without the GBA1 ...
Sofie Slingerland+6 more
wiley +1 more source
Trends in Incidence and Drug Prescriptions for Croup in Children Under 5 Years of Age: A 2002-2019 Population-Based Study. [PDF]
Kim BH+6 more
europepmc +1 more source