Results 231 to 240 of about 6,763,509 (345)

Mechanism‐Informed Language Modeling and Oxygenated 3D Screening Identify Berberine–Enzalutamide Synergy in Prostate Cancer Models

Advanced Science, EarlyView.
By integrating knowledge‐augmented artificial intelligence with an oxygen‐supplemented 3D screening platform, a synergistic interaction between berberine and enzalutamide is identified. The framework integrates compound mechanisms of action with disease‐relevant signaling context to prioritize candidate combinations and generate testable pathway‐based ...
Chih‐Hui Lo, Katie Shi, Lina Kafadarian, Alexandra Bermudez, Johnny Diaz, Liam Edwards, Yunqi Hong, Ziyi Chen, Hyeonji Hwang, Weihong Yan, Alan Levinson, Robert Damoiseaux, Cho‐Jui Hsieh, Tanya Stoyanova, Andrew S. Goldstein, Neil Y.C. Lin   +15 more
wiley   +1 more source

Association between sociodemographic status and antiepileptic drug prescriptions in children with epilepsy

Epilepsia, 2012
P. Mattsson, T. Tomson, Karin Edebol Eeg-Olofsson, L. Brännström, G. Ringbäck Weitoft   +4 more
semanticscholar   +1 more source

Prevalence of actionable pharmacogenetic variants and high-risk drug prescriptions: A Swiss hospital-based cohort study. [PDF]

Clin Transl Sci
Hodel F, Hodel F, De Min MB, Thorball CW, Redin C, Vollenweider P, Girardin F, Fellay J.   +7 more
europepmc   +1 more source

Advancing Biotherapeutic Treatment of Ulcerative Colitis Using Lipid Mesophases: Formulation Design and Preclinical Validation

Advanced Science, EarlyView.
Lipid mesophases provide a versatile platform for colon‐targeted delivery of biotherapeutics, protecting them from degradation while enhancing mucoadhesion and enabling localized, controlled release to the inflamed mucosa after oral or rectal administration. In a DSS‐induced colitis model, this strategy reduced disease activity, inflammatory biomarkers,
Rafaela Gazzi, Tiziana Cremona, Reto Czekalla, Emily Campbell, Marlene Schwarzfischer, Doris Pöhlmann, Vanessa Dobernig, Gerhard Rogler, Michael Scharl, Alessandra Bergadano, Raffaele Mezzenga, Martin Kuentz, Paola Luciani, Simone Aleandri   +13 more
wiley   +1 more source

Habitat‐Specific Design Strategies for Untethered Soft Robots

Advanced Science, EarlyView.
Habitat shapes the design of untethered soft robots. Across land, water, air, and living tissues, environmental constraints govern viable combinations of compliant structures, actuation mechanisms, and energy delivery. This review connects these constraints with robotic performance and identifies design principles for advancing adaptable, durable, and ...
Siyang Li, Zhikun Miao, Tuck‐Whye Wong, Tiefeng Li   +3 more
wiley   +1 more source

Exploring the influencing factors of non-insulin drug prescriptions in discharged patients with type 1 diabetes. [PDF]

Front Endocrinol (Lausanne)
Cheng Y, Li H, Liu X, Jin X, Han J, Du J, Xu C.   +6 more
europepmc   +1 more source

Prevalence and appropriateness of drug prescriptions for peptic ulcer and gastro-esophageal reflux disease in a cohort of hospitalized elderly.

European journal of internal medicine, 2011
L. Pasina, A. Nobili, M. Tettamanti, F. Salerno, S. Corrao, A. Marengoni, A. Iorio, Maura Marcucci, P. Mannucci   +8 more
semanticscholar   +1 more source

Snapshot Spatiotemporal‐Spectral Imaging Enabled by Joint Photonic Encoding

Advanced Science, EarlyView.
Spectra4D enables snapshot spatiotemporal‐spectral imaging by combining high‐speed DMD temporal modulation with CMOS‐integrated Fabry‐Pérot spectral encoding. From a single 2D measurement, a dual‐mask‐guided reconstruction network recovers multiple time‐resolved hyperspectral frames, enabling high‐fidelity observation of rapidly evolving spatial ...
Chunyu Chen, Junren Wen, Hao Sha, Chenying Yang, Ziyang Chen, Xiaochen Feng, Taiqin Chen, Wenzhen Zou, Xiangyu Chen, Xiangyang Ji, Guojun Liu, Yongbing Zhang   +11 more
wiley   +1 more source

Trends in Incidence and Drug Prescriptions for Croup in Children Under 5 Years of Age: A 2002-2019 Population-Based Study. [PDF]

J Korean Med Sci
Kim BH, Ha EK, Yoo H, Lee S, Rha YH, Han MY, Kim JH.   +6 more
europepmc   +1 more source

Pyrolyzed Photoresist as a Continuous‐Tone Mask for Grayscale Lithography

Advanced Science, EarlyView.
True grayscale contact photolithography masks are created by pyrolysis of 3D multiphoton resist patterns. The resulting carbon masks retain micrometer‐scale patterned features while providing continuous‐tone optical transmission. This approach provides access to high‐quality grayscale lithography without requiring exotic materials or commercial mask ...
Tielyr D. Creason, Gavin C. Gee, Zachary T. Piontkowski, Toai Ton‐That, Robert Reyna, Edward R. Arata, Mason Risley, Jacob D. Boissiere, Bryan Kaehr, D. Bruce Burckel   +9 more
wiley   +1 more source