Results 311 to 320 of about 4,176,223 (397)

Solanidine‐derived CYP2D6 phenotyping elucidates phenoconversion in multimedicated geriatric patients

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Phenoconversion, a genotype‐phenotype mismatch, challenges a successful implementation of personalized medicine. The aim of this study was to detect and determine phenoconversion using the solanidine metabolites 3,4‐seco‐solanidine‐3,4‐dioic acid (SSDA) and 4‐OH‐solanidine as diet‐derived cytochrome P450 2D6 (CYP2D6) biomarkers in a ...
Jens Andreas Sarömba, Julian Peter Müller, Jolanta Tupiec, Anjali Roeth, Berkan Kurt, Florian Kahles, Thea Laurentius, Cornelius Bollheimer, Julia C. Stingl, Katja S. Just   +9 more
wiley   +1 more source

Off-label drug prescriptions in French general practice: a cross-sectional study. [PDF]

BMJ Open, 2019
Drogou F, Netboute A, Giai J, Dode X, Darmon D, Kassai B, Letrilliart L.   +6 more
europepmc   +1 more source

Drug-induced symptoms of functional dyspepsia. A sequence symmetry analysis of 1.5 million prescriptions

, 2000
Peter Bytzer, Jesper Hallas
openalex   +1 more source

Utilization and expenditure on medicines for the management of osteoporosis in Ireland: A repeated cross‐sectional study

British Journal of Clinical Pharmacology, EarlyView.
Aim Osteoporosis is a prevalent skeletal disease characterized by low bone mass and increased fracture risk. Management of osteoporosis typically involves antiresorptive and anabolic therapies, which are reimbursed in Ireland through various drug schemes.
Amelia Smith, Lisa Kelly, Claire Gorry, Bernard Duggan, Michael Barry   +4 more
wiley   +1 more source

Understanding factors that influence the drug choice of prescribers: A Q‐methodology study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Introduction Therapeutic decision‐making often involves weighing several treatment options on the basis of, among other things, the disease profile, patient characteristics but also prescriber‐specific factors. This study investigated the factors influencing therapeutic decision‐making among prescribers and explores how these factors differ ...
Mariëlle G. Hartjes, Annelot E. F. Elsevier, Jan Willem Grijpma, Milan C. Richir, Michiel A. van Agtmael, Jelle Tichelaar   +5 more
wiley   +1 more source

Hepatitis C drug prescriptions and Medicaid policies--four states, Indian health care system, USA 2018. [PDF]

Int J Equity Health, 2019
Reilley B, Miller M, Hudson M, Haverkate R, Leston J.   +4 more
europepmc   +1 more source

Gender and Prescription Painkiller Misuse: Findings from the 2011 National Survey on Drug Use and Health

, 2000
Roger Clough
openalex   +2 more sources

Safety, tolerability, pharmacokinetics and pharmacodynamics of HSK31858, a novel oral dipeptidyl peptidase‐1 inhibitor, in healthy volunteers: An integrated phase 1, randomized, double‐blind, placebo‐controlled, single‐ and multiple‐ascending dose study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Dipeptidyl peptidase‐1 (DPP‐1) inhibitors have been studied for the treatment of neutrophil‐mediated inflammatory diseases including bronchiectasis, bronchial asthma and cystic fibrosis. This study evaluated the pharmacokinetics, pharmacodynamics, safety and tolerability of DPP‐1 inhibitor HSK31858 in healthy Chinese volunteers.
Yuhao Wang, Chao Yu, Mengyue Hu, Lu Wang, Meixia Chen, Hanmo Liu, Nan Wu, Jie Hou   +7 more
wiley   +1 more source

Lipid-lowering drug prescriptions in a group of Colombian patients. [PDF]

Biomedica, 2019
Gaviria-Mendoza A, Machado-Duque ME, Machado-Alba JE.   +2 more
europepmc   +1 more source

Antiepileptic drug utilization: a Danish prescription database analysis

, 2001
Per Rochat, Jesper Hallas, David Gaist, M. L. Friis   +3 more
openalex   +1 more source