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Current practice for diagnosing immediate drug hypersensitivity reactions in Korea [PDF]
Background/Aims Skin (STs) and drug provocation (DPTs) tests are essential for identifying the culprit drugs causing drug hypersensitivity reactions (DHRs).
Sung-Yoon Kang+3 more
doaj +1 more source
Background: Remimazolam besylate, a newly developed drug, is linked to various anaphylaxis cases. We present a case of remimazolam anaphylaxis confirmed using a provocation test.
Sangho Lee+7 more
doaj +1 more source
INTRODUCTION: There are conflicting results regarding the sensitivity of skin tests and cross-reactions between quinolones in quinolone allergy. In our study, we aimed to evaluate the results of skin tests and provocation tests performed with quinolones ...
Hale Ates+7 more
doaj +1 more source
Drug eruption by antihistamine mistaken for chronic urticaria in a child [PDF]
Although rare, antihistamines can cause adverse effects, including drug-induced eruptions or anaphylaxis. A 4-year-old child visited the pediatric department of a hospital for skin eruptions after administration of antihistamines, (e.g., ucerax ...
Gun Moo Lee+5 more
doaj +1 more source
Drug Allergy in Children: What Should We Know? [PDF]
The drug allergy “label” may have a lifetime of consequences for a child. Many children with alleged drug allergies are proven to be tolerant to the culprit medication when challenged.
Ji Soo Park, Dong In Suh
doaj +1 more source
Usefulness of drug provocation tests in children with a history of adverse drug reaction [PDF]
PurposeThere are very few reports of adverse drug reactions (ADR) and almost no study of drug provocation test (DPT) in Korean children. We aimed to assess the role of DPT in children with unpredictable ADRs, and compare the causative drugs and clinical ...
Hye Ran Na+3 more
doaj +1 more source
Generalized bullous fixed drug eruption (GBFDE) is a specific variant of fixed drug eruption that belongs to severe cutaneous adverse reactions (SCARs) and its diagnosis is based mainly on clinical course and especially on the reoccurrence of typical ...
Michael Makris+5 more
doaj +1 more source
Drug allergy evaluation in children with suspected mild antibiotic allergy
BackgroundAdverse antibiotic reactions caused by an immunological mechanism are known as allergic reactions. The percentage of reported antibiotic allergies is likely to differ from the one validated after a drug provocation test (DPT) with the culprit ...
Nikolaos Kitsos+7 more
doaj +1 more source
DCcov: Repositioning of Drugs and Drug Combinations for SARS-CoV-2 Infected Lung through Constraint-Based Modelling [PDF]
The 2019 coronavirus disease (COVID-19) became a worldwide pandemic with currently no effective antiviral drug except treatments for symptomatic therapy. Flux balance analysis is an efficient method to analyze metabolic networks. It allows optimizing for a metabolic function and thus e.g., predicting the growth rate of a specific cell or the production
arxiv +1 more source
The state and consideration for skin test of β-lactam antibiotics in pediatrics
β-lactam antibiotics are the most frequently used drugs and the most common drugs that cause allergic reactions in pediatrics. The occurrence of some allergic reactions can be predicted by skin testing, especially severe adverse reactions such as ...
Chunhui Gao+3 more
doaj +1 more source