Pro and Contra: Provocation Tests in Drug Hypersensitivity [PDF]
Drug provocation test (DPT) is the controlled administration of a drug to diagnose immune- or non-immune-mediated drug hypersensitivity and the last step for accurate recognition of drug hypersensitivity reactions when the previous diagnostic evaluations
O. Soyer, U. Sahiner, B. Sekerel
semanticscholar +4 more sources
Cross‐Reactive NSAID Hypersensitivity: Clinical Findings From Aspirin Provocation and Alternative Drug Challenge Testing [PDF]
Nonsteroidal anti‐inflammatory drug (NSAID) hypersensitivity reactions are commonly reported but often overestimated due to reliance on clinical history alone.
Young‐Il Koh, Ji Eun Yu, Da Woon Sim
doaj +2 more sources
Drug provocation tests: up-date and novel approaches [PDF]
Drug provocation tests (DPTs) are often needed when evaluating patients with suspected drug hypersensitivity reactions. General considerations on DPTs, with regard to indications, contraindications, methods, limitations and interpretations have been thoroughly addressed and various protocols are published. However, the field of drug allergy is changing
Anca Mirela Chiriac, Pascal Demoly
openalex +6 more sources
Evaluating the Effect of Drug Provocation Tests on Anxiety and Hopelessness Levels [PDF]
Background and Objectives: Drug provocation tests (DPTs) diagnose drug hypersensitivity reactions (DHRs) and identify safe alternatives. DHRs contribute to patient anxiety.
Gürgün Tuğçe Vural Solak +10 more
doaj +2 more sources
Diagnostics of cutaneous adverse drug reactions: evaluation of patch tests, lymphocyte transformation tests, and drug provocation tests [PDF]
BackgroundPatch tests (PT) and/or lymphocyte transformation tests (LTT) are typically performed, when diagnosed with cutaneous adverse drug reactions (CADR). However, their positivity rates can vary depending on the rash type.
Tomomu Ishikawa +5 more
doaj +2 more sources
Two Cases of Anaphylaxis to Tranexamic Acid Confirmed by Drug Provocation Test: What About Skin Testsing? [PDF]
Hassan El Hanache +8 more
openalex +2 more sources
Pulmonary tuberculosis (PTB) continues to be a public health problem, especially in developing countries. The necessity use of multidrug regimens of antituberculosis drug (ATD) in PTB treatment has been associated with increased risk of drug ...
KETUT SURYANA
openalex +3 more sources
Fluoroquinolones are a commonly prescribed class of antibiotics due to their broad spectrum of antimicrobial activity, favorable pharmacokinetic properties, ability to switch from parenteral to oral administration, and global availability.
Marija Kurtov +7 more
doaj +2 more sources
Effectiveness and safety of algorithm for treating pregnant women with syphilis and history of immediate allergy to penicillin [PDF]
Background: Penicillin is the only proven effective treatment for pregnant women with syphilis. Objective: We evaluated the efficacy and safety of an algorithm to guide reexposure to penicillin in pregnant women with syphilis and a history of allergy to ...
Bruna Gehlen, MD +5 more
doaj +2 more sources
Oral drug provocation test to generate a list of safe drugs: Experience with 100 patients
BACKGROUND Following a drug eruption, patients and their doctors need to know which drugs can be safely administered for subsequent illnesses. Currently available laboratory tests are unable to answer this question in a clinically meaningful manner ...
M Ramam +3 more
openalex +3 more sources

