Qualitative study of stakeholder perspectives on dementia policy implementation in Macao: progress, challenges and future directions. [PDF]
Zheng Y +5 more
europepmc +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
'I want to be generous, but I only have limited energy': a qualitative study of amyotrophic lateral sclerosis patients' preferences for clinical trials participation. [PDF]
Adeagbo MJ +4 more
europepmc +1 more source
openaire +1 more source
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
What might influence the elderly willingness to participate in "shared elderly care"? A mixed methods study. [PDF]
Wan H +6 more
europepmc +1 more source
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Effects of multi-disciplinary team nursing model combined with high-fiber dietary intervention on blood glucose level and nutritional status in elderly type 2 diabetes patients: a prospective clinical trial. [PDF]
Wang H, Yan M, Wang H, He L, Zhang Y.
europepmc +1 more source
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye +11 more
wiley +1 more source
Retrospective analysis of U.S. Food and Drug Administration recalls of artificial tear solutions from 2014 to 2025. [PDF]
Bhattacharya A, Kang PC.
europepmc +1 more source

