Results 1 to 10 of about 9,770,479 (402)

Fatal anaphylactic shock following cefoperazone–sulbactam re-exposure: a short report on systemic gaps in adverse drug reaction management [PDF]

BMJ Open Quality
This report presents a case of fatal anaphylactic shock following re-exposure to cefoperazone-sulbactam, highlighting systemic gaps in adverse drug reaction (ADR) management.
LiLi Xu, Xiaomei Mo, Guanhua Liang, Wenhui Gan, Meixing Yan   +4 more
doaj   +2 more sources

The Drug Reaction Problem

The American Journal of Digestive Diseases, 1967
Henry J. Tumen, John V. Carbone, Albert I. Mendeloff, Fenton Schaffner, Hyman J. Zimmerman   +4 more
openalex   +6 more sources

Safety and effectiveness of all-oral and injectable-containing, bedaquiline-based long treatment regimen for pre-XDR tuberculosis in Vietnam

Frontiers in Pharmacology, 2022
Background: The World health organization (WHO) recently recommended standardized all-oral shorter regimens for rifampicin resistant Tuberculosis (RR-TB).
Thi Mai Phuong Nguyen, Binh Hoa Nguyen, Thi Thanh Thuy Hoang, Hoang Anh Nguyen, Dinh Hoa Vu, Mai Hoa Nguyen, Bao Ngoc Nguyen, Tom Decroo, Viet Nhung Nguyen   +8 more
doaj   +1 more source

Drug Reaction with Eosinophilia and Systemic Symptoms (DReSS)/Drug-Induced Hypersensitivity Syndrome (DiHS)—Readdressing the DReSS

Biomedicines, 2022
Drug reaction with eosinophilia and systemic symptoms (DReSS), also known as drug-induced hypersensitivity syndrome (DiHS), is a severe, systemic, T cell mediated drug reaction with combinations of cutaneous, hematologic, and internal organ involvement ...
H. Stirton, N. Shear, R. Dodiuk-Gad
semanticscholar   +1 more source

The Russian Drug Reaction Corpus and Neural Models for Drug Reactions and Effectiveness Detection in User Reviews [PDF]

Bioinform., 2020
MOTIVATION Drugs and diseases play a central role in many areas of biomedical research and healthcare. Aggregating knowledge about these entities across a broader range of domains and languages is critical for information extraction (IE) applications. In
E. Tutubalina, I. Alimova, Z. Miftahutdinov, Andrey Sakhovskiy, Valentin Malykh, S. Nikolenko   +5 more
semanticscholar   +1 more source

Validation of Artificial Intelligence to Support the Automatic Coding of Patient Adverse Drug Reaction Reports, Using Nationwide Pharmacovigilance Data

Drug Safety, 2022
Introduction Adverse drug reaction reports are usually manually assessed by pharmacovigilance experts to detect safety signals associated with drugs.
Guillaume L. Martin, Julien Jouganous, Romain Savidan, Axel Bellec, C. Goehrs, M. Benkebil, G. Miremont, J. Micallef, F. Salvo, A. Pariente, L. Létinier   +10 more
semanticscholar   +1 more source

Novel Therapeutic Targets in Liver Fibrosis

Frontiers in Molecular Biosciences, 2021
Liver fibrosis is end-stage liver disease that can be rescued. If irritation continues due to viral infection, schistosomiasis and alcoholism, liver fibrosis can progress to liver cirrhosis and even cancer.
Jinhang Zhang, Qinhui Liu, Jinhan He, Jinhan He, Yanping Li   +4 more
doaj   +1 more source

Current Perspective Regarding the Immunopathogenesis of Drug-Induced Hypersensitivity Syndrome/Drug Reaction with Eosinophilia and Systemic Symptoms (DIHS/DRESS)

International Journal of Molecular Sciences, 2021
Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms (DIHS/DRESS) is a severe type of adverse drug eruption associated with multiorgan involvement and the reactivation of human herpesvirus 6, which arises after ...
F. Miyagawa, H. Asada
semanticscholar   +1 more source

Inhibition of 5-Lipoxygenase in Hepatic Stellate Cells Alleviates Liver Fibrosis

Frontiers in Pharmacology, 2021
Background and Purpose: Activation of hepatic stellate cells (HSC) is a central driver of liver fibrosis. 5-lipoxygenase (5-LO) is the key enzyme that catalyzes arachidonic acid into leukotrienes.
Shiyun Pu, Shiyun Pu, Yanping Li, Qinhui Liu, Xu Zhang, Lei Chen, Lei Chen, Rui Li, Rui Li, Jinhang Zhang, Jinhang Zhang, Tong Wu, Tong Wu, Qin Tang, Qin Tang, Xuping Yang, Xuping Yang, Zijing Zhang, Zijing Zhang, Ya Huang, Ya Huang, Jiangying Kuang, Jiangying Kuang, Hong Li, Hong Li, Min Zou, Wei Jiang, Jinhan He, Jinhan He   +28 more
doaj   +1 more source

Study of prescribing errors of two different prescription systems: pre-printed prescription from historical medication and hand-written prescription [PDF]

Pharmaceutical Sciences Asia, 2022
A retrospective observational study of 1,160 prescriptions with prescribing errors from a large academic hospital in Thailand from 2014 to 2017. The aims of this study are to explore the proportion of prescribing error from pre-printed prescriptions and ...
Nisa Sae-lim, Ploylarp Lertvipapath
doaj   +1 more source