Results 91 to 100 of about 4,801,266 (265)

Drug induced renal diseases

, 1994
Nephrotoxicity complicates the use of many different pharmacological agents. Up to 20 % of cases of acute renal failure can be directly attributed to drugs.
Wang, A. Y M, Lai, K. N.
core  

Plasmodium falciparum population dynamics during the early phase of anti-malarial drug treatment in Tanzanian children with acute uncomplicated malaria. [PDF]

, 2011
BACKGROUND\ud \ud This study aimed to explore Plasmodium falciparum population dynamics during the early phase of anti-malarial drug treatment with artemisinin-based combination therapy in children with clinical malaria in a high transmission area in ...
Carlsson, A.M, Abdulla, Salim, Christopher Membi, Veiga, I.M, Ngasala, Billy E, Gil, J Pedro, Abdulla, S., Carlsson, Anja M, Premji, Z., Björkman, Anders, Premji, Zul, Dahlström, Sabina, Veiga, I.M., Carlsson, Anja M., Anders Björkman, Abdulla Salim, Ngasala, B.E, Lars Rombo, Billy E Ngasala, Veiga, Isabel M, Gil, J. P., Björkman Anders, Zul Premji, Membi, Christopher, Mårtensson, Andreas, Ngasala, Billy E., Bjorkman, A., Martensson, A., Salim Abdulla, Isabel M Veiga, Mårtensson Andreas, Gil J, Ngasala Billy E, Gil, J.P., Rombo, L., Premji Zul, Rombo Lars, Carlsson Anja M, Andreas Mårtensson, Membi Christopher, Anja M Carlsson, Dahlstrom, S., Membi, C., Rombo, Lars,, Carlsson, A.M., Sabina Dahlström, J Gil, Dahlström Sabina, Veiga, Maria Isabel, Rombo, Lars, Veiga Isabel M, Ngasala, B.E.   +51 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Perspectives on drugs: Drug consumption rooms: an overview of provision and evidence. [PDF]

, 2016
Supervised drug consumption facilities, where illicit drugs can be used under the supervision of trained staff, have been operating in Europe for the last three decades.

core  

Clinical relevance of drug-drug interactions : a structured assessment procedure. [PDF]

, 2005
Item does not contain fulltextINTRODUCTION: Computerised drug interaction surveillance systems (CIS) may be helpful in detecting clinically significant drug interactions. Experience with CIS reveals that they often yield alerts with questionable clinical
Flikweert, S., Langendijk, PNJ, Smits, P, le Comte, M., Brouwers, J.R.B.J., van Roon, EN; id_orcid, Roon, E.N. van, Langendijk, P.N., Kwee-Zuiderdijk, W.J.M., Brouwers, JRBJ, Flikweert, S, van Roon, E.N., van Roon, EN, Comte, M. le, le Comte, M, Kwee-Zuiderwijk, WJM, Smits, P., Kwee-Zuiderwijk, W.J., Langendijk, P.J.N.   +18 more
core   +2 more sources

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Perspectives on drugs: Internet-based drug treatment. [PDF]

, 2014
The Internet is now recognised as a plausible vehicle for delivering drug and alcohol education, prevention and treatment programmes in a range of settings.

core  

Fixed Eruptions: Drug, food, and what more?

Clinical Dermatology Review
Fixed drug eruption (FDE) is a common entity encountered in our day-to-day clinical practice. It is a T-cell-dependent pathway with induction of interferon-gamma-producing CD8+ T-cells in the dermis and epidermis.
Prabhakar Mallikarjuna Sangolli, Neethu Mary George   +1 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Polysaccharides in Ocular Drug Delivery [PDF]

, 2019
Polysaccharides, such as cellulose, hyaluronic acid, alginic acid, and chitosan, as well as polysaccharide derivatives, have been successfully used to augment drug delivery in the treatment of ocular pathologies.
Arto Urtti, Skorik, Yury A., Yury A. Skorik, Poshina, Daria, Urtti, Arto, Dubashynskaya, Natallia, Raik, Sergei, Sergei Raik, Daria Poshina, Natallia Dubashynskaya   +9 more
core   +1 more source