Results 101 to 110 of about 4,801,266 (265)

Acute generalized exanthematous pustulosis induced by iodinated contrast media: a case report

open access: yesDermatology Reports
Acute generalized exanthematous pustulosis (AGEP) is a rare pustular eruption commonly triggered by drugs. It’s characterized by acute onset of pustules on erythematous-edematous skin and often presents with fever.
Maisa Alfalah   +3 more
doaj   +1 more source

Vemurafenib-associated neutrophilic panniculitis in a patient with metastatic amelanotic melanoma presenting as cancer of unknown primary origin

open access: yesDermatologica Sinica, 2016
The treatment of metastatic melanoma is challenging. BRAF gene mutation is found in 40–60% of melanoma cases, the most common being the V600E mutation.
Yu-Ching Weng   +5 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Significant geographical differences in prevalence of mutations associated with Plasmodium falciparum and Plasmodium vivax drug resistance in two regions from Papua New Guinea [PDF]

open access: yes, 2015
Drug resistance remains a major obstacle to malaria treatment and control. It can arise and spread rapidly, and vary substantially even at sub-national level.
Jonah Iga (175169)   +32 more
core   +1 more source

Case Report: Azathioprine-induced Sweet’s syndrome with associated myocardial infarction

open access: yesFrontiers in Medicine
Sweet’s syndrome (SS) is an acute febrile neutrophilic dermatosis characterized by a rash with tender erythematous plaques or nodules, fevers and leukocytosis.
Natalie Commins   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Ana Liffey Drug Project annual report 1993

open access: yes, 1994
I note that the Project commenced in 1982 and since that time the range and level of services has been developed significantly. The Project was established at a time when the need for services for people with HIV/AIDS had not become apparent and it ...
Ana Liffey Drug Project
core  

Diagnosis of drug induced liver injury using a lymphocyte blast transformation test based on whole blood culture [PDF]

open access: yes, 1977
Twenty cases of suspected drug induced liver injury (16 cases of which satisfied the criteria for at least a query positive diagnosis as based on the Fourth Congress of "Drugs and the Liver" in Japan) were studied by the whole blood culture ...
Takata, Shinji
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

The global drug survey 2015

open access: yes, 2015
This survey attracted more than 100,000 on line responses from individuals around the world about their drug use. The study looked at prevalence, price, purity, value for money and the proportion of people seeking medical treatment.
Global Drug Survey
core  

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