Results 121 to 130 of about 1,787,106 (336)

Drug Hypersensitivity Syndrome toCarbamazepine and Human Herpes Virus 6 Infection: Case Reportand Literature Review [PDF]

, 2018
.: We describe a patient with a drug-induced hypersensitivity syndrome to carbamazepine and a concomitant active infection with human herpes virus 6 (HHV-6).
Battegay, E., Bircher, A., Hirsch, H., Schaub, N., Steffen, I., Zeller, A.   +5 more
core  

Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction. [PDF]

, 1977
Bertil Hille
openalex   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Ocular reaction to propranolol and resolution on continued treatment with a different beta-blocking drug. [PDF]

, 1975
R B Cubey, S. H. Taylor
openalex   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Fixed Eruptions: Drug, food, and what more?

Clinical Dermatology Review
Fixed drug eruption (FDE) is a common entity encountered in our day-to-day clinical practice. It is a T-cell-dependent pathway with induction of interferon-gamma-producing CD8+ T-cells in the dermis and epidermis.
Prabhakar Mallikarjuna Sangolli, Neethu Mary George   +1 more
doaj   +1 more source

Observations on the Reactions of the Larvae of Ancylostoma canium and Ancylostoma braziliense to Various Drugs and Chemical Compounds Based on In Vitro Tests

, 1953
EARL B. RITCHIE, William C. King
openalex   +1 more source

Adverse drug reaction bulletin [PDF]

, 1971

openalex   +1 more source

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

Molecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan, Moshe Leitner, Amos Toren, Shoshana Paglin, Michal Yalon   +4 more
wiley   +1 more source

Drug reactions characterized by cholestasis associated with intrahepatic biliary tract obstruction

, 1957
Alexander B. Gutman
openalex   +1 more source