Results 121 to 130 of about 996,854 (268)

Pyoderma gangrenosum developing in a patient treated with dupilumab

JAAD Case Reports, 2022
Jessica Nasseh, MD, Henry Abi Rached, MD, Ioana Dumitru, MD, Delphine Staumont-Sallé, MD, PhD, Frédéric Dezoteux, MD   +4 more
doaj   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Cutaneous drug reaction induced by enfortumab-vedotin. [PDF]

CMAJ
Gretschel L, Wetzel E, Mittank-Weidner T.   +2 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

A pattern of serious adverse drug reactions reported in a tertiary care hospital, Rangaraya Medical College, Kakinada, Andhra Pradesh

, 2020
Sweta Bindu Mendu, K. V. Siva Prasad
openalex   +2 more sources

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Pseudoephedrine-Associated Erythromelalgia: A Case Report of a Rare Drug Reaction. [PDF]

Case Rep Dermatol
Wong LZ, Kravvas G.
europepmc   +1 more source

Non-Immediate Type Hypersensitivity Reactions with First-Line Antituberculosis Drugs and Diagnostic Patch Testing

Gözde Köycü Buhari, Sakine Nazik Bahçecioğlu, Selcan Gültuna, Dilek Çuhadar Erçelebi, Şenay Demir, Hatice Çelik Tuğlu, Onur Telli, Kurtuluş Aksu   +7 more
openalex   +1 more source

Relationships between serum vitamin D levels and clinical characteristics of drug reaction with eosinophilia and systemic symptoms syndrome

, 2013
Mi-Ran Park, Young‐Hee Nam, Il-Hwan Jeong, Hye Won Lee, Yong Jun Kim, In‐Chul Park, Duk-Song Cho, Neul-Bom Yoon, Soo‐Jung Um, Choon-Hee Son, Soo-Keol Lee   +10 more
openalex   +1 more source