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Drug Hypersensitivity Reactions
Emergency Medicine Clinics of North America, 2022Drug hypersensitivity reactions are a diverse group of reactions mediated by the immune system after exposure to a drug. The Gell and Coombs classification divides immunologic DHRs into 4 major pathophysiologic categories based on immunologic mechanism. Anaphylaxis is a Type I hypersensitivity reaction that requires immediate recognition and treatment.
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Immunology and Allergy Clinics of North America, 2004
Cutaneous drug reactions have a variety of clinical presentations. This review focuses on the most common or severe cutaneous reaction patterns. Knowledge of the clinical morphology and the most commonly associated medication aids in rapid diagnosis and institution of the appropriate therapy.
Jeffrey K, McKenna, Kristin M, Leiferman
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Cutaneous drug reactions have a variety of clinical presentations. This review focuses on the most common or severe cutaneous reaction patterns. Knowledge of the clinical morphology and the most commonly associated medication aids in rapid diagnosis and institution of the appropriate therapy.
Jeffrey K, McKenna, Kristin M, Leiferman
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The American Journal of Cardiology, 1963
I N GENERAL, reactions from drugs are usually classified as (1) allergic causing symptoms of anaphylaxis, (2) side actions causing undesirable responses apart from the main therapeutic goal, and (3) delayed toxicity causing varied pathologic syndromes usually associated with the peculiar metabolism of the drug.
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I N GENERAL, reactions from drugs are usually classified as (1) allergic causing symptoms of anaphylaxis, (2) side actions causing undesirable responses apart from the main therapeutic goal, and (3) delayed toxicity causing varied pathologic syndromes usually associated with the peculiar metabolism of the drug.
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Journal of the American Academy of Dermatology, 1986
R S, Stern, B U, Wintroub, K A, Arndt
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R S, Stern, B U, Wintroub, K A, Arndt
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Drug Reactions to the Sulfones
Archives of Dermatology, 1970In a brief temporal span, two patients treated with diaminodiphenyl sulfone had significant reactions to the drug. These were severe hemolysis and the hitherto undescribed reaction of cholestatic jaundice. Review of the literature in regards to indications for sulfone therapy and the drug-associated reactions was accomplished.
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