Results 21 to 30 of about 9,770,479 (402)

Sirt6 in pro-opiomelanocortin neurons controls energy metabolism by modulating leptin signaling

Molecular Metabolism, 2020
Objective: Sirt6 is an essential regulator of energy metabolism in multiple peripheral tissues. However, the direct role of Sirt6 in the hypothalamus, specifically pro-opiomelanocortin (POMC) neurons, controlling energy balance has not been established ...
Qin Tang, Yong Gao, Qinhui Liu, Xuping Yang, Tong Wu, Cuiyuan Huang, Ya Huang, Jinhang Zhang, Zijing Zhang, Rui Li, Shiyun Pu, Guorong Zhang, Yingnan Zhao, Jian Zhou, Hui Huang, Yanping Li, Wei Jiang, Yongsheng Chang, Jinhan He   +18 more
doaj   +1 more source

Sol–gel synthesis and thermal behavior of bioactive ferrous citrate–silica hybrid materials [PDF]

, 2018
Imbalance of the iron level in the body causes several diseases. In particular, the low level of iron, during pregnancy, is responsible for the iron deficiency anemia, and even of neurodegenerative diseases.
Catauro, M., Naviglio, D., Risoluti, R., Vecchio, Ciprioti   +3 more
core   +1 more source

Study of adverse drug reactions of atypical antipsychotic drugs in the department of psychiatry in a tertiary care hospital of Assam

Open Journal of Psychiatry and Allied Sciences, 2017
Objective: To monitor the adverse drug reactions (ADRs) of atypical antipsychotic drugs in the outpatient department (OPD) of psychiatry in Silchar Medical College and Hospital (SMCH) of Assam, and also to find out the causality and severity of ADRs ...
Pinaki Chakravarty, Parthajyoti Neog, Babul Dewan   +2 more
doaj   +1 more source

One-pot multi-reaction processes: synthesis of natural products and drug-like scaffolds [PDF]

, 2014
One-pot multi-reaction processes involving Overman rearrangements, metathesis cyclizations, and Diels–Alder reactions have been developed for the rapid and efficient synthesis of amino-substituted carbocyclic and heterocyclic compounds.
Calder, Ewen D.D., Grafton, Mark W., Sutherland, Andrew   +2 more
core   +1 more source

Valproic acid-induced eosinophilic pleural effusion: An uncommon occurrence

Lung India, 2023
A 43-year-old male using valproic acid (VA) for 2 years for seizure disorder presented with right-sided moderate pleural effusion. Pleural fluid analysis revealed exudative effusion with 42% eosinophils. There was no evidence of haemothorax, pneumothorax,
Manisha Bhardwaj, Pratibha Himral, Surender Kashyap   +2 more
doaj   +1 more source

Healthcare professionals’ pharmacovigilance knowledge and adverse drug reaction reporting behavior and factors determining the reporting rates

Journal of Drug Assessment, 2019
Background: Spontaneous adverse drug reaction (ADR) reports prepared by healthcare professionals (HCPs) are the backbone of collecting post-marketing safety data.
M. Güner, P. Ekmekci
semanticscholar   +1 more source

Semi-Supervised Recurrent Neural Network for Adverse Drug Reaction mention extraction [PDF]

BMC Bioinformatics, 2017
Social media is a useful platform to share health-related information due to its vast reach. This makes it a good candidate for public-health monitoring tasks, specifically for pharmacovigilance.
Shashank Gupta, Sachin Sharad Pawar, Nitin Ramrakhiyani, Girish Keshav Palshikar, Vasudeva Varma   +4 more
semanticscholar   +1 more source

The Role of Sirt6 in Obesity and Diabetes

Frontiers in Physiology, 2018
Sirt6 is one of the sirtuin family members, a kind of NAD+-dependent histone deacetylase and ADP-ribose transferase enzyme. It has an important role in physiological and pathological processes, regulating aging, cancer, obesity, insulin resistance ...
Jiangying Kuang, Jiangying Kuang, Lei Chen, Lei Chen, Qin Tang, Qin Tang, Jinhang Zhang, Jinhang Zhang, Yanping Li, Yanping Li, Jinhan He, Jinhan He   +11 more
doaj   +1 more source

Facile one-pot synthesis of amoxicillin-coated gold nanoparticles and their antimicrobial activity [PDF]

, 2014
Nanomaterials have been the object of intense study due to promising applications in a number of different disciplines. In particular, medicine and biology have seen the potential of these novel materials with their nanoscale properties for use in ...
A Fleming, A Kumar, A Rai, B Duncan, CK Kim, D Pissuwan, E Boisselier, G Frens, H Gu, HC Neu, J Turkevich, JD Gibson, KB Holten, M Brust, M De, MC Daniel, MN Martin, P Ghosh, RA Sperling, V Sambhy   +19 more
core   +1 more source

DRESS: características clinicopatológicas em 10 casos de Hospital Universitário em São Paulo [PDF]

, 2012
BACKGROUND: Drug reaction with eosinophilia and systemic symptoms is a severe form of drug-induced reaction with multiorgan involvement. OBJECTIVES: The aim of this study is to evaluate the epidemiological, clinical and pathological features and ...
Botelho, Luciane Francisca Fernandes, Enokihara, Mílvia Maria Simões e Silva, Higashi, Viviane Shinsato, Padilha, Maria Helena Valle de Queiroz, Porro, Adriana Maria   +4 more
core   +4 more sources