Results 51 to 60 of about 4,801,266 (265)

Enoxaparin‐induced bullous hemorrhagic dermatosis at a distant location from the injection site

open access: yesClinical Case Reports, 2021
Heparin‐induced bullous hemorrhagic dermatosis is a benign and self‐limited condition. However, it might cause significant patient frustration. Clinicians should be aware of this rare adverse reaction.
Abdulrahman F. Al‐Mashdali   +1 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Rituximab therapy for Severe and Persistent Lichenoid drug-reaction [PDF]

open access: yes, 2019
We report on a patient with severe and fixed lichenoid drug-reaction.  She did not respond to 2 months treatment with high-dose corticosteroids.  Hence, Rituximab was given.  One month later, her lesions improved and remained stable for 14
El-Reshaid, Kamel, Al-Bader, Shaima
core   +1 more source

Hemin coupled protein biomimetic nanozymes combining confinement effects for sensitive chemiluminescence immunoassay

open access: yesChemPhysMater
Nanozymes offer superior stability and resistance to deactivation while mimicking the catalytic activity of natural enzymes, thereby expanding their applications across various fields.
Tong Jiang   +5 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Brief strategic family therapy for adolescent drug abuse. [PDF]

open access: yes, 2003
To ensure that treatment providers apply the most current scientifically supported approaches to their patients, NIDA has supported the development of the "Therapy Manuals for Drug Addiction" series.

core  

Evaluation of drug release kinetics from ibuprofen matrix tablets using HPMC. [PDF]

open access: yes, 2006
The aim of this study is to develop a once-daily sustained release matrix tablet of ibuprofen using hydroxypropyl methylcellulose (HPMC) as release controlling factor and to evaluate drug release parameters as per various release kinetic models. In order
Tazeen, Jaweria   +3 more
core   +3 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

National drug-related public expenditure online resource.

open access: yes, 2021
This is the first set of national profiles that the EMCDDA has produced on drug-related public expenditure. The profiles are based on the sections on public expenditure provided by the 27 EU Member States, Croatia, Turkey and Norway in the national ...

core  

Cytomegalovirus infection initiates inflammatory bowel disease by activating a positive MyD88/NF-κB feedback loop in allogeneic skin transplantation mice

open access: yesVirology Journal
Infection with the cytomegalovirus (CMV) is common. Inflammatory bowel disease (IBD) is characterized by chronic inflammation in the gastrointestinal tract. CMV infection is involved in IBD pathogenesis. The abnormal activation of myeloid differentiation
Ming-Xian Chen   +5 more
doaj   +1 more source

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