Results 61 to 70 of about 9,770,479 (402)

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

Enoxaparin‐induced bullous hemorrhagic dermatosis at a distant location from the injection site

open access: yesClinical Case Reports, 2021
Heparin‐induced bullous hemorrhagic dermatosis is a benign and self‐limited condition. However, it might cause significant patient frustration. Clinicians should be aware of this rare adverse reaction.
Abdulrahman F. Al‐Mashdali   +1 more
doaj   +1 more source

Kejadian Reaksi Obat Yang Tidak Dikehendaki Yang Menyebabkan Pasien Usia Lanjut Dirawat Di Ruang Perawatan Penyakit Dalam Instalasi Rawat Inap B Rumah Sakit Dr. Cipto Mangunkusumo [PDF]

open access: yes, 2008
Objectives. To determine the prevalence of adverse drug reaction related hospital ad-missions in geriatric patients, to describe the most frequent clinical manifestationsand the drugs responsible to adverse drug reaction related hospital admissions ...
Andrajati, R. (Retnosari)   +3 more
core  

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles. [PDF]

open access: yes, 2017
Treatment of dyslipidemia patients with lipid-lowering drugs leads to a significant reduction in low-density lipoproteins (LDL) level and a low to moderate level of increase in high-density lipoprotein (HDL) cholesterol in plasma.
Alderete, Benjamin   +7 more
core   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

How to promote adverse drug reaction reports using information systems – a systematic review and meta-analysis

open access: yesBMC Medical Informatics and Decision Making, 2016
BackgroundAdverse drug reactions (ADRs) are a well-recognized public health problem and a major cause of death and hospitalization in developed countries.
I. Ribeiro-Vaz   +3 more
semanticscholar   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

Adverse Drug Reaction Classification With Deep Neural Networks [PDF]

open access: yes, 2016
We study the problem of detecting sentences describing adverse drug reactions (ADRs) and frame the problem as binary classification. We investigate different neural network (NN) architectures for ADR classification.
He, Yulan   +3 more
core   +1 more source

An annotated corpus with nanomedicine and pharmacokinetic parameters [PDF]

open access: yes, 2017
A vast amount of data on nanomedicines is being generated and published, and natural language processing (NLP) approaches can automate the extraction of unstructured text-based data. Annotated corpora are a key resource for NLP and information extraction
Jimenez, Ivan   +2 more
core   +2 more sources

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