Results 151 to 160 of about 26,660 (305)

A case-based explainable graph neural network framework for mechanistic drug repositioning. [PDF]

Bioinformatics
Gonzalez-Cavazos AC, Tu R, Sinha M, Su AI.   +3 more
europepmc   +1 more source

Review of nutrition management of pediatric intestinal pseudo‐obstruction

Nutrition in Clinical Practice, EarlyView.
Abstract Chronic intestinal pseudo‐obstruction (CIPO) is a rare, heterogeneous, and debilitating disorder characterized by profound intestinal dysmotility and severe nutrition challenges. Its presentation resembles that of mechanical bowel obstruction, but CIPO occurs in the absence of luminal obstruction.
Senthilkumar Sankararaman, Raisa Rani James, Bushra El‐Amaireh, Andrea Adler, Kadakkal Radhakrishnan, Sujithra Velayuthan   +5 more
wiley   +1 more source

Link Prediction in Multipartite Graphs With Application to Drug Repositioning Studies. [PDF]

IEEE Trans Comput Biol Bioinform
Chen C, Grady SK, Dojcsak L, Ellingson SR, Langston MA.   +4 more
europepmc   +1 more source

Drug Repositioning for Alzheimer’s Disease: A Delphi Consensus and Stakeholder Consultation

Janet Sultana, Clive Ballard, Kate Stych, Kathryn Mills, Anne Corbett   +4 more
openalex   +1 more source

Increased expression of aromatase after focal cerebral ischemia: Relevance to neuroprotection and functional recovery

Neuroprotection, EarlyView.
Abstract Aim Aromatase is the key enzyme in the biosynthesis of 17β‐estradiol, the most potent estrogen, which has pleiotropic neuroprotective properties. Aromatase levels increase in the brain after stroke, and its gene variants increase susceptibility to stroke. This study aims to determine whether aromatase overexpression improves stroke outcome and
Lindsay Gallagher, Anna F. Dominiczak, Luis M. Garcia‐Segura, Nobuhiro Harada, J. B. Hutchison, James M. Mullin, Delyth Graham, Peter O'Shaughnessy, Hilary Victoria O. Carswell   +8 more
wiley   +1 more source

A fused deep learning approach to transform drug repositioning. [PDF]

Commun Chem
Li K, Yi J, Ye Q, Yang X, Yu L, Deng Y, Wu C, Hou T, Jiang D, Cao D.   +9 more
europepmc   +1 more source

Aging-related Repositioned Drugs, Donepezil and Sildenafil Citrate, Increase Apoptosis of Anti-mitotic Drug-resistant KBV20C Cells Through Different Molecular Mechanisms [PDF]

, 2018
Ji Yeong Kim, Ji Yeon Son, Byung‐Mu Lee, Hyung Sik Kim, Sungpil Yoon   +4 more
openalex   +1 more source

Procedural‐Based Contemporary Management of Bell's Palsy Long‐Term Sequelae: A Narrative Review

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To describe the long‐term sequelae of Bell's palsy and summarize available treatment options, including recent advances, so that general otolaryngologists and other practitioners are aware of the clinical findings and available interventions. Data Sources PubMed.
Robert M. Frederick, Rhorie Kerr, Eric Dobratz, William Dougherty   +3 more
wiley   +1 more source

Drug Repositioning in Doxorubicin-Induced Cardiotoxicity Protection. [PDF]

Int J Mol Sci
Kosić M, Pajović V, Jovanović M, Japundžić-Žigon N.   +3 more
europepmc   +1 more source

Repositioning Proton Pump Inhibitors as Anticancer Drugs by Targeting the Thioesterase Domain of Human Fatty Acid Synthase

, 2014
Valerie Fako, Xi Wu, Beth R. Pflug, Jing-Yuan Liu, Jian‐Ting Zhang   +4 more
openalex   +2 more sources