Results 301 to 310 of about 60,427 (345)
Improving drug repositioning with negative data labeling using large language models. [PDF]
Picard M +5 more
europepmc +1 more source
Drug Repositioning for Cancer Treatment : Novel Candidate Identification Strategies
Madiha Nazir
openalex +1 more source
Drug repositioning for pan-cancers of the digestive system: Identification of amonafide and BX795 as potential therapeutics via integrative Omics analysis. [PDF]
Liu W, Gao J, Ren S, Nashun B, Gao F.
europepmc +1 more source
Repositioning Drugs for Psychiatry.
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Drug repositioning for Alzheimer's disease
Nature Reviews Drug Discovery, 2012Existing drugs for Alzheimer's disease provide symptomatic benefit for up to 12 months, but there are no approved disease-modifying therapies. Given the recent failures of various novel disease-modifying therapies in clinical trials, a complementary strategy based on repositioning drugs that are approved for other indications could be attractive ...
Corbett, Anne +17 more
openaire +6 more sources
Drug Repositioning in Oncology
American Journal of Therapeutics, 2021Background: The worldwide increase in the occurrence of cancer associated with the limitations of immunotherapy and the emergence of resistance have impaired the prognosis of cancer patients, which leads to the search for alternative treatment methods.
Marissa B, Serafin +7 more
openaire +2 more sources
Journal of Chemical Information and Modeling, 2020
Drug repositioning aims to reuse "old" drugs to treat diseases outside their approved indication(s). Composition-of-matter patents and FDA exclusivities can hinder the immediate availability of some drugs to be repositioned (repurposed). Here, we analyze data from the FDA Orange Book and use current on-market patent validity and exclusivities to ...
Sorin Avram +4 more
openaire +3 more sources
Drug repositioning aims to reuse "old" drugs to treat diseases outside their approved indication(s). Composition-of-matter patents and FDA exclusivities can hinder the immediate availability of some drugs to be repositioned (repurposed). Here, we analyze data from the FDA Orange Book and use current on-market patent validity and exclusivities to ...
Sorin Avram +4 more
openaire +3 more sources
Network-based drug repositioning
Molecular BioSystems, 2013Network-based computational biology, with the emphasis on biomolecular interactions and omics-data integration, has had success in drug development and created new directions such as drug repositioning and drug combination. Drug repositioning, i.e., revealing a drug's new roles, is increasingly attracting much attention from the pharmaceutical ...
Zikai, Wu, Yong, Wang, Luonan, Chen
openaire +2 more sources

