Dental Traumatology, EarlyView.ABSTRACT Background/Aims To evaluate the prevalence and timing of post‐operative complications following tooth autotransplantation, identify factors associated with earlier diagnosis, and report long‐term survival and success rates. Materials and Methods A single‐centre retrospective cohort study was conducted at a Czech university dental clinic (2003 ...
Juraj Marton +5 more
wiley +1 more source
Using systems biology and drug repositioning approaches to discover FDA-approved drugs candidates for endometriosis treatment. [PDF]
PLoS OneSanami S +6 more
europepmc +1 more source
Balancer‐assisted sling recovery of critical equine patients after general anaesthesia
Equine Veterinary Education, EarlyView.Summary Background Traditional sling‐based systems to assist horses during recovery from general anaesthesia (GA) could be improved by adding a balancer to obtain a dynamic weight relief. Objectives To evaluate the applicability of a novel balancer‐assisted sling system during recovery of horses after GA and to report initial experiences with high‐risk
J. Kuhlmann, C. Spadavecchia, C. Koch
wiley +1 more source
Translational Informatics Driven Drug Repositioning for Neurodegenerative Disease. [PDF]
Curr NeuropharmacolZheng X +8 more
europepmc +1 more source
Surgical management of recurrent oesophageal obstruction in a yearling Saddlebred filly
Equine Veterinary Education, EarlyView.Summary This case report describes the diagnostic approach and surgical management of a yearling Saddlebred filly with recurrent oesophageal obstruction, likely caused by an acquired extraluminal oesophageal stricture. The filly initially presented with repeated episodes of oesophageal obstruction, which were resolved with sedation and nasogastric ...
K. M. Andrews +4 more
wiley +1 more source
Recent advances in drug repositioning and rediscovery for different therapeutic activities utilizing updated technological approaches. [PDF]
Mol DiversNossier ES, Anwar MM, El-Zahabi MA.
europepmc +1 more source
Human IDO2 exhibits unique binding affinities distinct to those of human IDO1
The FEBS Journal, EarlyView.Although indoleamine 2,3‐dioxygenase 2 (IDO2) is highly homologous to IDO1, it displays markedly lower catalytic activity. We found that IDO2 binds L‐tryptophan (L‐Trp) in a flipped orientation stabilized by the IDO2‐specific residue His143. Replacement of His143 with the IDO1‐equivalent tyrosine restored an IDO1‐like binding mode and increased ...
Shunsuke Nogi +8 more
wiley +1 more source
Drug repositioning pipeline integrating community analysis in drug-drug similarity networks and automated ATC community labeling to foster molecular docking analysis. [PDF]
Front BioinformColibăşanu D +5 more
europepmc +1 more source
International Journal of Cosmetic Science, EarlyView.Photo grading of dynamic lines in the dynamic line repeatability validation study. Abstract Objective This study aimed to develop and validate a novel, integrated dynamic wrinkle assessment system based on standardized, real‐time and multi‐angle facial images and video recordings, and to explore its potential application in evaluating the anti‐wrinkle ...
Xingzuo Liu +6 more
wiley +1 more source