Results 91 to 100 of about 3,841,835 (347)

Drug Repurposing of Selected Antibiotics: An Emerging Approach in Cancer Drug Discovery

open access: yesACS Omega
Drug repurposing is a method of investigating new therapeutic applications for previously approved medications. This repurposing approach to “old” medications is now highly efficient, simple to arrange, and cost-effective and poses little risk of failure
Nilofer Bano   +5 more
semanticscholar   +1 more source

Bioprinted Constructs in the Regulatory Landscape: Current State and Future Perspectives

open access: yesAdvanced Materials, EarlyView.
Bioprinting has rapidly emerged as a transformative technology in biomedical research, offering unprecedented potential to replicate complex tissues. Despite its promise, clinical translation remains limited due to regulatory hurdles. This review explores global regulatory frameworks, comparing approaches in the EU, U.S., China, and Australia, and ...
Francesca Perin   +6 more
wiley   +1 more source

Drug Repurposing in the Chemotherapy of Infectious Diseases

open access: yesMolecules
Repurposing is a universal mechanism for innovation, from the evolution of feathers to the invention of Velcro tape. Repurposing is particularly attractive for drug development, given that it costs more than a billion dollars and takes longer than ten ...
Amal Hamid, Pascal Mäser, A. Mahmoud
semanticscholar   +1 more source

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

open access: yesAdvanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi   +4 more
wiley   +1 more source

Sustainable Liquid Metal Composites for Soft Electronics and E‐Waste Reduction

open access: yesAdvanced Materials, EarlyView.
Liquid metal (LM) composites embody recyclability, repairability, renewability, and resilience (4R), offering a sustainable route for soft electronics. With exceptional conductivity, stretchability, and eco‐friendly recovery, these systems enable closed‐loop lifecycles and reduce e‐waste.
Abdollah Hajalilou   +2 more
wiley   +1 more source

Computational repurposing of oncology drugs through off‐target drug binding interactions from pharmacological databases

open access: yesClinical and Translational Medicine
Purpose Systematic repurposing of approved medicines for another indication may accelerate drug development in oncology. We present a strategy combining biomarker testing with drug repurposing to identify new treatments for patients with advanced cancer.
Imogen R. Walpole   +8 more
doaj   +1 more source

Drug repurposing with network reinforcement

open access: yesBMC Bioinformatics, 2019
Drug repurposing has been motivated to ameliorate low probability of success in drug discovery. For the recent decade, many in silico attempts have received primary attention as a first step to alleviate the high cost and longevity. Such study has taken benefits of abundance, variety, and easy accessibility of pharmaceutical and biomedical data ...
Yonghyun Nam   +3 more
openaire   +3 more sources

Liquid‐in‐Liquid Prints: High‐Density Biochemically Encoded Information Preserved in Microdroplet Arrays

open access: yesAdvanced Materials, EarlyView.
This work introduces a novel approach for encoding and storing information in the liquid state in microdroplet arrays. These liquid‐in‐liquid prints are generated by a droplet printing system capable of dynamically setting the composition of each droplet pixel.
Maximilian Breitfeld   +5 more
wiley   +1 more source

Identifying patterns to uncover the importance of biological pathways on known drug repurposing scenarios

open access: yesBMC Genomics
Background Drug repurposing plays a significant role in providing effective treatments for certain diseases faster and more cost-effectively. Successful repurposing cases are mostly supported by a classical paradigm that stems from de novo drug ...
Belén Otero-Carrasco   +5 more
doaj   +1 more source

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