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Drug Repurposing for Rare Diseases [PDF]
Trends in Pharmacological Sciences, 2021 Currently, there are about 7000 identified rare diseases, together affecting 10% of the population. However, fewer than 6% of all rare diseases have an approved treatment option, highlighting their tremendous unmet needs in drug development. The process of repurposing drugs for new indications, compared with the development of novel orphan drugs, is a ...
Helen I Roessler +2 more
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Perspectives on Drug Repurposing
Current Medicinal Chemistry, 2021Complex common diseases are a significant burden for our societies and demand not only preventive measures but also more effective, safer, and more affordable treatments. The whole process of the current model of drug discovery and development implies a high investment by the pharmaceutical industry, which ultimately impact in high drug prices.
Alejandro Schcolnik-Cabrera +2 more
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2022
Drug repurposing is the process of finding new therapeutic applications for previously used, available or older medications. Drug repurposing, refers to a set of approaches that aim to adapt the current pharmacological effects to new applications. Repurposing can help uncover new medicines for diseases at a low cost and in less time.
Dr Gyansagar Kushwaha +3 more
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Drug repurposing is the process of finding new therapeutic applications for previously used, available or older medications. Drug repurposing, refers to a set of approaches that aim to adapt the current pharmacological effects to new applications. Repurposing can help uncover new medicines for diseases at a low cost and in less time.
Dr Gyansagar Kushwaha +3 more
+5 more sources
Drug databases and their contributions to drug repurposing
Genomics, 2020 Drug repurposing is an interesting field in the drug discovery scope because of reducing time and cost. It is also considered as an appropriate method for finding medications for orphan and rare diseases. Hence, many researchers have proposed novel methods based on databases which contain different information.
Yosef Masoudi-Sobhanzadeh +2 more
exaly +3 more sources
JAMA Psychiatry
This Viewpoint discusses a proposal to identify candidates for drug repurposing and allocate US Food and Drug Administration funds to cover the cost of evaluating and approving such drugs for their novel indications.
Peter, Nagele +2 more
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This Viewpoint discusses a proposal to identify candidates for drug repurposing and allocate US Food and Drug Administration funds to cover the cost of evaluating and approving such drugs for their novel indications.
Peter, Nagele +2 more
openaire +2 more sources
2023
This data set examines the practice of repurposing drugs for multiple therapeutic purposes, which is a persistent 'innovation' strategy in the pharmaceutical industry.
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This data set examines the practice of repurposing drugs for multiple therapeutic purposes, which is a persistent 'innovation' strategy in the pharmaceutical industry.
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In the dynamic landscape of cancer therapeutics, the innovative strategy of drug repurposing emerges as a transformative paradigm, heralding a new era in the fight against malignancies. This book chapter aims to embark on the comprehension of the strategic deployment of approved drugs for repurposing and the meticulous journey of drug repurposing from ...
Juni, Banerjee +2 more
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Juni, Banerjee +2 more
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An overview to drug repurposing
Identification and implementation of novel drug are not only time consuming and expensive but also it poses huge challenge to reach into the market. Currently, thousands of USFDA approved drugs licence are being expired that can be repurposed for treating other diseases.Khushal, Khambhati +2 more
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Journal of Prescribing Practice
In this month's article, George Winter discusses the potential for repurposed drugs to change the therapeutic landscape
Duilio Cervantes, Aida Adlimoghaddam
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In this month's article, George Winter discusses the potential for repurposed drugs to change the therapeutic landscape
Duilio Cervantes, Aida Adlimoghaddam
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Drug Repurposing Based on Drug–Drug Interaction
Chemical Biology & Drug Design, 2014Given the high risk and lengthy procedure of traditional drug development, drug repurposing is gaining more and more attention. Although many types of drug information have been used to repurpose drugs, drug–drug interaction data, which imply possible physiological effects or targets of drugs, remain unexploited.
Bin, Zhou +3 more
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