Results 181 to 190 of about 629,459 (301)

[Applications of molecularly imprinted solid-phase microextraction coupled with chromatography/mass spectrometry for determination of drug residues]. [PDF]

Se Pu
Yan J, Huang J, Peng S, Man M, Sun D, Liu P, Chen L, Li J, Fan H.   +8 more
europepmc   +1 more source

One Health antimicrobial resistance research coordinating workshop [PDF]

, 2020
International Livestock Research Institute
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

A green and verified high-performance liquid chromatographic technique for the concurrent measurement of a few veterinary drug residues in milk. [PDF]

BMC Chem
Abdel Sattar OI, Abuseada HHM, Emara MS, Rabee M.   +3 more
europepmc   +1 more source

[Determination of 41 veterinary drug residues in livestock and poultry meat using a composite purification system coupled with direct analysis in real time-tandem mass spectrometry]. [PDF]

Se Pu, 2023
Xie YS, Wang B, Lei CN, Liu LX, Zhang H, Bai XB, Kou ZH.   +6 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Non-Targeted Screening and Quantitative Analysis of Pesticides and Veterinary Drug Residues in <i>Brassica rapa chinensis</i> Using an Improved Quechers Method Based on Magnetic Materials. [PDF]

Foods
Tang M, Ni Y, Zang T, Gao W, Song J, Zou J, Xu D.   +6 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Veterinary Drug Residues in Food Products of Animal Origin and Their Public Health Consequences: A Review. [PDF]

Vet Med Sci
Mesfin YM, Mitiku BA, Tamrat Admasu H.
europepmc   +1 more source

Validated Simultaneous Gradient Ultra-Performance Liquid Chromatographic Quantification of Some Proton Pump Inhibitor Drug Residues in Saudi Pharmaceutical Industrial Wastewater. [PDF]

Molecules, 2021
Abdel-Gawad SA, Arab HH, Alabbas AB.
europepmc   +1 more source