Results 111 to 120 of about 544,638 (287)
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley +1 more source
A Scientific Roadmap for Antibiotic Discovery: A Sustained and Robust Pipeline of New Antibacterial Drugs and Therapies is Critical to Preserve Public Health [PDF]
In recent decades, the discovery and development of new antibiotics have slowed dramatically as scientific barriers to drug discovery, regulatory challenges, and diminishing returns on investment have led major drug companies to scale back or abandon ...
Allan Coukell+5 more
core
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana+2 more
wiley +1 more source
GENETIC AND BIOCHEMICAL STUDIES OF BACTERIAL DRUG RESISTANCE
Many papers have been presented on the enzymatic inactivation of the aminoglycosidic antibiotics by cell-free extracts obtained from drug-resistant strains of bacteria isolated from clinical specimens. Kanamycin is inactivated by two mechanisms responsible for the formation of 6-N-acetyl-kanamycin and 3'-phosphorylkanamycin.
openaire +3 more sources
The temporary transition of macrophages from a pro‐inflammatory phenotype of macrophages (M1) to an anti‐inflammatory phenotype of macrophages (M2) is crucial for tissue repair and regeneration processes. Bacterial outer membrane vesicles (OMVs) are utilized as a “trojan horse” for specific M1 macrophage‐targeting and anti‐inflammatory drug delivery ...
Donglin Cai+9 more
wiley +1 more source
Anti Microbial Resistance Profile of E. coli isolates From Tropical Free Range Chickens [PDF]
Normal intestinal flora of humans and animals constitute enormous reservoir of resistance genes for potentially pathogenic bacteria and may serve as major indictors of selection pressure exerted by anti-microbial use in a given population.
A BI, Udedibie+3 more
core +1 more source
Biopolymers are sustainable, biodegradable alternatives to petroleum‐based plastics for food packaging. Its adoption is often limited by poor mechanical strength, barrier properties, and improved thermal stability through the incorporation of nanofillers.
Himakshi Baishya+2 more
wiley +1 more source
Background VanB-type vancomycin (VAN) resistance gene clusters confer VAN resistances on Enterococcus spp. over a wide range of MIC levels (MIC = 4–1000 mg/L).
Yusuke Hashimoto+8 more
doaj +1 more source
In this article, Hojin Kim, Sayan Deb Dutta, and co‐workers report a shape‐reconfigurable, 3D printable, and highly adhesive slime‐like ‘electronic skin’ or ‘E‐skin’ patch for human health sensing and tissue engineering applications. The dual reinforcement of hydrogel patch with carbon nanotubes (CNTs) and cellulose nanocrystals (CNCs) improve the ...
Hojin Kim+6 more
wiley +1 more source
Transforming Cellulose Into Functional Three‐Dimensional Structures
Cellulose is promising for replacing synthetic polymers due to its excellent mechanical properties and low cost. This review highlights the recent advancements in transforming cellulose into functional 3D structures, including liquid gels and porous materials.
Xia Sun+5 more
wiley +1 more source