Results 91 to 100 of about 4,798,630 (303)
The Association between Mycobacterium Tuberculosis Genotype and Drug Resistance in Peru.
PLoS ONE, 2015 BackgroundThe comparison of Mycobacterium tuberculosis bacterial genotypes with phenotypic, demographic, geospatial and clinical data improves our understanding of how strain lineage influences the development of drug-resistance and the spread of ...
Louis Grandjean +17 more
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Defence against bacterial drug resistance. [PDF]
BMJ, 1976 Everyone knows that acquired microbic resistance is the Achilles heel of chemotherapy. All living things can acquire some resistance to noxious agents-man to morphine, for instance. Bacteria are no exception: they can become more resistant in some degree even to ordinary germicides.
openaire +2 more sources
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Interventions on Metabolism: Making Antibiotic-Susceptible Bacteria
mBio, 2017 Antibiotics act on bacterial metabolism, and antibiotic resistance involves changes in this metabolism. Interventions on metabolism with drugs might therefore modify drug susceptibility and drug resistance.
Fernando Baquero, José-Luis Martínez
doaj +1 more source
FEBS Open Bio, EarlyView.In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
Multi-Drug Resistance Bacterial Infections in Critically Ill Patients Admitted with COVID-19. [PDF]
Microorganisms, 2021 Pasero D, Cossu AP, Terragni P.
europepmc +1 more source
Drugs Repurposing for Multi-Drug Resistant Bacterial Infections
, 2020 Different institutions recognized that antimicrobial resistance is a global health threat that has compounded by the reduction in the discovery and development of new antimicrobial agents. Therefore, the development of new antimicrobial therapeutic strategies requires immediate attention to avoid the 10 million deaths predicted to occur by 2050 as a ...
Andrea Vila Domínguez +2 more
openaire +2 more sources
FEBS Open Bio, EarlyView.Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta +7 more
wiley +1 more source
F1000Research, 2019 Bacterial infections involving antibiotic-resistant gram-negative bacteria continue to increase and represent a major global public health concern.
Dickson Aruhomukama +2 more
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