Integration of computational and experimental approaches for deciphering the underlying mechanism of biomolecular condensates and potential biomaterials design (Created in Biorender. Raza, Z. (2025) https://BioRender.com/irgmeqi). Abstract Biomolecular condensates, a ubiquitous class of biomaterials found in living cells, have been shown to be ...
Qiang Zhu+10 more
wiley +1 more source
Nanotherapies based on bacterial metabolism: Mechanisms, design and application. [PDF]
Chen J+13 more
europepmc +1 more source
Spatially Controlled 3‐D Multiplexed Aptamer Patterning in Hydrogels
A hydrogel platform based on norbornene‐functionalized polyvinyl alcohol enables high‐resolution, 3‐D multiplexed patterning of DNA aptamers via two‐photon polymerization. Two distinct aptamers are covalently immobilized with single micron‐scale precision across the x, y, and z dimensions.
Kevin Roost+9 more
wiley +1 more source
Mechanistic studies on the effect of berberine on methicillin-resistant Staphylococcus aureus drug resistance through modulation of wall teichoteic acid. [PDF]
Zhou F+8 more
europepmc +1 more source
Supported lipid bilayers coupled with multielectrode array devices offer significant promise for pathogen–host cell membrane interaction studies. This work demonstrates, for the first time, the compatibility of this platform with biological fluids, in this case whole human blood, essential for any future point‐of‐care applications; as well as its ...
Alexandra Wheeler+4 more
wiley +1 more source
Isolation, Identification, and Antibiotic Resistance, CRISPR System Analysis of <i>Escherichia coli</i> from Forest Musk Deer in Western China. [PDF]
Yang K+8 more
europepmc +1 more source
Preferential Membrane Remodeling on Curved Biointerfaces Induced by Conjugated Oligoelectrolyte
This study explores how membrane shape influences the interaction of conjugated oligoelectrolytes (COEs) with lipid bilayers. Using a curved biointerface composed of nanobar arrays and supported lipid bilayers, it is revealed that COE intercalation preferentially remodels curved regions, forming distinct structures. These findings highlight the role of
Xinwen Miao+7 more
wiley +1 more source
A Mechanistic Approach to Replacing Antibiotics with Natural Products in the Treatment of Bacterial Diarrhea. [PDF]
Wei M+7 more
europepmc +1 more source
Photo‐iniferter polymerization is used to create antimicrobial polymers which are decorated with sugar units by either copolymerization of glycomonomers or post‐polymerization functionalization. Although a selectivity based on lectin binding can not be observed, the presence of sugar leads to improved bioactivity based on the presence of neutral ...
Alain M. Bapolisi+10 more
wiley +1 more source
Comparative Effects of Intermittent vs. Constant Ceftiofur Hydrochloride Exposure on <i>Staphylococcus aureus</i> In Vitro. [PDF]
Wang J, Li C, Guo F, Yu Z.
europepmc +1 more source