Results 261 to 270 of about 780,165 (288)
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EMERGENCE OF DRUG RESISTANCE

Infectious Disease Clinics of North America, 1999
Antimicrobial resistance has emerged among the three major bacterial pathogens causing meningitis. Chloramphenicol resistance in the meningococcus recently has been described, and although intermediate penicillin resistance is common in some countries, the clinical importance of penicillin resistance in the meningococcus has yet to be established. Beta-
Shabir A. Madhi, Keith P. Klugman
openaire   +3 more sources

Impact of Drug Resistance on Virulence and Fitness of Bacterial Pathogens

Critical Care Medicine, 2016
International ...
Roux, Damien   +5 more
openaire   +5 more sources

Bacterial Genotypic Drug Resistance Assays

2017
The increasing emergence of antimicrobial multiresistance has significantly reduced the therapeutic options available for treating common bacterial infections. We are facing a serious worldwide health crisis but, paradoxically, this is also an exciting time since the rapid evolution of genomic technologies has facilitated the development of molecular ...
Michel G. Bergeron, Ann Huletsky
openaire   +2 more sources

Bacterial drug-resistance

Molecular Genetics, Microbiology and Virology (Russian)
Genetic control of different pathways of drug-resistance formation in bacteria is presented. Possible molecular mechanisms of “new” genes integration into the genomes by horizontal gene transfer are discussed. This review may be valuable for physicians, veterinarians and scientific researches engaged in bacterial evolution.
openaire   +1 more source

Antimicrobial activity of nanoemulsion on drug-resistant bacterial pathogens

Microbial Pathogenesis, 2018
The appearance of drug-resistant (DR) bacteria in the community is a crucial development, and is associated with increased morbidity, mortality, healthcare costs, and antibiotic use. Natural oil nanoemulsions (NEs) have potential for antimicrobial applications. In the present study, we determined the antimicrobial activity of an NE against DR bacterial
Rajapandiyan Krishnamoorthy   +6 more
openaire   +2 more sources

Detection and characterization of bacterial polysaccharides in drug-resistant enterococci

Glycoconjugate Journal, 2019
Enterococcus faecium (E. faecium) has emerged as one of today's leading causes of health care-associated infections that is difficult to treat with the available antibiotics. These pathogens produce capsular polysaccharides on the cell surface which play a significant role in adhesion, virulence and evasion.
Ali, Liaqat   +2 more
openaire   +4 more sources

A Bacterial Model System for Understanding Multi-Drug Resistance

Microbial Drug Resistance, 1997
Mankind stands at the crossroads, recognizing the need for a radical change in bacterial disease management. The development of several antimicrobial agents in the 1940s and 1950s allowed man to gain the upper hand in controlling these diseases. However, the horizon is now clouded by the activation in bacteria of cryptic multi-drug resistance (MDR ...
Abdul Matin   +3 more
openaire   +2 more sources

CHALLENGES OF BACTERIAL DRUG RESISTANCE IN DEVELOPING COUNTRIES

2017
Ethiopian Journal of Health and Biomedical Sciences, Vol. 8 No.
openaire   +2 more sources

Bacterial quorum sensing inhibitors: attractive alternatives for control of infectious pathogens showing multiple drug resistance.

Recent Patents on Anti-Infective Drug Discovery, 2013
Quorum sensing (QS) is a bacterial communication process that depends on the bacterial population density. It involves small diffusible signaling molecules which activate the expression of myriad genes that control diverse array of functions like ...
A. Bhardwaj   +2 more
semanticscholar   +1 more source

The role played by drug efflux pumps in bacterial multidrug resistance.

Essays in Biochemistry, 2017
Antimicrobial resistance is a current major challenge in chemotherapy and infection control. The ability of bacterial and eukaryotic cells to recognize and pump toxic compounds from within the cell to the environment before they reach their targets is ...
M. Chitsaz, Melissa H. Brown
semanticscholar   +1 more source

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