Results 241 to 250 of about 4,798,630 (303)

PEAR1 Promotes Glucose Metabolism Reprogramming in Sepsis‐Associated Acute Lung Injury via AARS1‐Mediated HIF‐1α Lactylation

Advanced Science, EarlyView.
This study revealed that a PEAR1/HIF‐1α/ glycolysis/lactate/H3K18la positive feedback loop in PMVECs that drives the development of S‐ALI. Mechanistically, PEAR1 mediates the binding of HIF‐1α to AARS1, leading to the lactylation of HIF‐1α, the primary lactylation site of which is K172.
Shuai Li, Zongqing Lu, Pu Fang, Qingqing Pang, Xianghui Wu, Bo Wang, Min Liang, Jingjing Pan, Haobo Kong, Haijian Cai, Juanjuan Li, Jiaying Kang, Dongsheng Wang, Dunling Xia, Mengmeng Xu, Qinghai You   +15 more
wiley   +1 more source

Defensins as natural antimicrobial peptide scaffolds against antimicrobial-resistant pathogens: mechanisms, resistance risks, and translational prospects. [PDF]

Front Cell Infect Microbiol
Abdallah EM, Al-Mijalli SH, Al Hakawati N, Al Khatib A.   +3 more
europepmc   +1 more source

Liposome drug delivery strategies: state-of-the-art for combating bacterial biofilms. [PDF]

Front Microbiol
Lin T, Liu H, He W, Hu W, Jiang H, Xu Z, Wei J, Yang M, Dai H, Xu J.   +9 more
europepmc   +1 more source

High Burden of Multidrug-Resistant Bacteria in Eastern Democratic Republic of the Congo: A Retrospective Hospital-Based Study. [PDF]

Infect Drug Resist
Kabagale Ansima C, Iragi Mulume G, Jibu Maroyi B, Alanga Murhabazi S, Kalume Kamwanga K, Mulumeoderwa Badesire A, Raharisoa Dina P, Ntabala Lwabaguma E, Hendwa Kashinja E, Ongezi Lurhangire E, Cubaka Kabagale A, Lupande Mwenebitu D.   +11 more
europepmc   +1 more source

Current and emerging biomaterials for targeted drug delivery in osteomyelitis management. [PDF]

Discov Nano
Rajendran P, Sekar R, Ali EM, Dayasankar PS, Abdallah BM.   +4 more
europepmc   +1 more source

Molecular Epidemiology and Multilevel Drug Resistance Mechanisms of <i>Escherichia coli</i> in the Context of One Health: A Comprehensive Narrative Review. [PDF]

Infect Drug Resist
Liu M, Liu L, Fu H, Li X, Wang Y, Xu B.
europepmc   +1 more source

Detection of carbapenem resistance mechanisms in difficult-to-treat Pseudomonas aeruginosa clinical isolates from a tertiary care hospital in Egypt. [PDF]

BMC Microbiol
Salem D, Zaiton M, El-Shenawy A, Dahroug H, El-Dein S, Gamal D, Althoqapy AA, Mohamed AA, Shemis MA, Diab M, Maklad SS.   +10 more
europepmc   +1 more source

[Drug therapy of infections and bacterial resistance].

Boletin medico del Hospital Infantil de Mexico, 1978
openaire   +1 more source

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Drugs Resistance in Bacterial Diseases

2021
The development of resistance in micro-organisms against the antimicrobial agents is known as drug resistance, and this causes morbidity and mortality in humans and animals. Major contributing factors for the development of drug resistance are the overuse of antibiotics, inaccurate implementation, extended hospitalization, and unintended prescriptions.
Muhammad Zeeshan Ahmed, Tazeen Rao, Waqas Ahmad, Shahzeb Hameed, Samrana Anayat, Asma Altaq, Wafa Iqbal, Muhammad Younus, Ali Ahmad, Suvash Chandra Ojha, Atif Liaqat, Rahat Naseer, Shehla Munir, Muhammad Ibrahim, Sarfraz Ahmed   +14 more
openaire   +1 more source

Observations on the drug resistance of bacterial recombinants

Proceedings of the Royal Society of London. Series B - Biological Sciences, 1959
Abstract Strains of Escherichia coli ‘K-12’, sensitive or resistant to chloramphenicol, proflavine or brilliant green were crossed, and the drug resistance of the recombinant strains examined. For this purpose a quantitative scale of resistance was established, so that the spectrum of the distribution among the recombinants could be ...
G W, BARTLETT, C, HINSHELWOOD
openaire   +2 more sources