Results 61 to 70 of about 1,077,335 (347)

Airborne Multidrug-Resistant Bacteria Isolated from a Concentrated Swine Feeding Operation [PDF]

, 2004
The use of nontherapeutic levels of antibiotics in swine production can select for antibiotic resistance in commensal and pathogenic bacteria in swine. As a result, retail pork products, as well as surface and groundwaters contaminated with swine waste ...
Amy Chapin, Ana Rule, Jensen LB, Kellogg Schwab, Kristen Gibson, Mackiewicz B, Timothy Buckley, Zahn JA   +7 more
core   +2 more sources

Major bacterial isolate and antibiotic resistance from routine clinical samples in Southern Ethiopia

Scientific Reports, 2021
Currently, antibiotic-resistant bacterial infections are a challenge for the health care system. Although physicians demand timely drug resistance data to guide empirical treatment, local data is rather scarce. Hence, this study performed a retrospective
Mengistu Hailemariam, Tsegaye Alemayehu, Bereket Tadesse, Netsanete Nigussie, Asnakech Agegnehu, Techilo Habtemariam, Mulubrhan Ali, Enkosilassie Mitiku, Elshaday Azerefegne   +8 more
doaj   +1 more source

Rapid decline of bacterial drug-resistance in an antibiotic-free environment through phenotypic reversion

eLife, 2019
Antibiotic resistance typically induces a fitness cost that shapes the fate of antibiotic-resistant bacterial populations. However, the cost of resistance can be mitigated by compensatory mutations elsewhere in the genome, and therefore the loss of ...
Anett Dunai, Réka Spohn, Z. Farkas, Viktória Lázár, Adam Gyorkei, G. Apjok, G. Boross, Balázs Szappanos, Gábor Grézal, Anikó Faragó, L. Bodai, Balázs Papp, Csaba Pál   +12 more
semanticscholar   +1 more source

Drugs Repurposing for Multi-Drug Resistant Bacterial Infections

, 2020
Different institutions recognized that antimicrobial resistance is a global health threat that has compounded by the reduction in the discovery and development of new antimicrobial agents. Therefore, the development of new antimicrobial therapeutic strategies requires immediate attention to avoid the 10 million deaths predicted to occur by 2050 as a ...
Andrea Vila Domínguez, Younes Smani, Manuel Mejías   +2 more
openaire   +3 more sources

Strategies to Combat Multi-Drug Resistance in Tuberculosis

Accounts of Chemical Research, 2021
Conspectus “Drug resistance is an unavoidable consequence of the use of drugs; however, the emergence of multi-drug resistance can be managed by accurate diagnosis and tailor-made regimens.” Antimicrobial resistance (AMR), is one of the most paramount ...
Vinayak Singh, K. Chibale
semanticscholar   +1 more source

Role of xenobiotic transporters in bacterial drug resistance and virulence [PDF]

IUBMB Life, 2008
AbstractSince the discovery of antibiotic therapeutics, the battles between humans and infectious diseases have never been stopped. Humans always face the appearance of a new bacterial drug‐resistant strain followed by new antibiotic development. However, as the genome sequences of infectious bacteria have been gradually determined, a completely new ...
Akihito Yamaguchi, Kunihiko Nishino, Kunihiko Nishino   +2 more
openaire   +3 more sources

Whole-Genome Sequencing and Concordance Between Antimicrobial Susceptibility Genotypes and Phenotypes of Bacterial Isolates Associated with Bovine Respiratory Disease. [PDF]

, 2017
Extended laboratory culture and antimicrobial susceptibility testing timelines hinder rapid species identification and susceptibility profiling of bacterial pathogens associated with bovine respiratory disease, the most prevalent cause of cattle ...
Abdo, Zaid, Aly, Sharif S, Belk, Keith, Blanchard, Patricia C, Davis, Jessica H, Lehenbauer, Terry W, Miller, Michael R, Morley, Paul, Noyes, Noelle, O'Rourke, Sean M, Owen, Joseph R, Prince, Daniel J, Van Eenennaam, Alison L, Young, Amy E   +13 more
core   +2 more sources

Antimicrobial Resistance in Commensal Flora of Pig Farmers

Emerging Infectious Diseases, 2004
We assessed the quantitative contribution of pig farming to antimicrobial resistance in the commensal flora of pig farmers by comparing 113 healthy pig farmers from the major French porcine production areas to 113 nonfarmers, each matched for sex, age ...
Hélène Aubry-Damon, Karine Grenet, Penda Sall-Ndiaye, Didier Che, Eugenio Cordeiro, Marie-Elisabeth Bougnoux, Emma Rigaud, Yann Le Strat, Véronique Lemanissier, Laurence Armand-Lefèvre, Didier Delzescaux, Jean-Claude Desenclos, Michel Liénard, Antoine Andremont   +13 more
doaj   +1 more source

In Silico Screen Identifies a New Family of Agonists for the Bacterial Mechanosensitive Channel MscL

Antibiotics, 2022
MscL is a highly conserved mechanosensitive channel found in the majority of bacterial species, including pathogens. It functions as a biological emergency release valve, jettisoning solutes from the cytoplasm upon acute hypoosmotic stress.
Robin Wray, Paul Blount, Junmei Wang, Irene Iscla   +3 more
doaj   +1 more source

Review on Multiple Facets of Drug Resistance: A Rising Challenge in the 21st Century

Journal of Xenobiotics, 2021
With the advancements of science, antibiotics have emerged as an amazing gift to the human and animal healthcare sectors for the treatment of bacterial infections and other diseases.
M. Saha, Agniswar Sarkar
semanticscholar   +1 more source