Results 131 to 140 of about 330,368 (263)

Challenges and innovations in resistance, remediation, and regulation: key findings from the spring 2025 ASM Theobald Smith Society meeting. [PDF]

mSphere
Lumkong L, Nyiro B, Russo S, Westervelt I, Sullivan RF, Boyd JM, Carabetta VJ, Yadavalli SS, Sun JS.   +8 more
europepmc   +1 more source

The Interplay between the Gut and Ketogenic Diets in Health and Disease

Advanced Science, EarlyView.
This review synthesizes current knowledge on the interaction between ketogenic diets and the gut, covering gut physiology, intestinal immunity, and the gut microbiome. It explores innovative methods for tailoring the diet to maximize benefits while reducing side effects. Emphasis is placed on gut‐mediated mechanisms as a critical interface between diet
Chunlong Mu, Jong M. Rho, Jane Shearer
wiley   +1 more source

Beyond breakpoint - reconceptualising AMR as a symptom of planetary stress. [PDF]

NPJ Antimicrob Resist
Kirchhelle C, Roberts AP.
europepmc   +1 more source

Gut Parabacteroides distasonis‐derived Indole‐3‐Acetic Acid Promotes Phospholipid Remodeling and Enhances Ferroptosis Sensitivity via the AhR‐FASN Axis in Bladder Cancer

Advanced Science, EarlyView.
Indole‐3‐acetic acid (3‐IAA) derived from gut P. distasonis binds to AhR in bladder cancer cells and downregulates FASN transcription, thereby increasing sensitivity to ferroptosis and suppressing the development of bladder tumors. Specifically, 3‐IAA treatment leads to an increase in the proportion of PC/PE‐PUFAs and a decrease in the proportions of ...
Weijia Li, Wentai Shangguan, Wenxue Huang, Jie Zhao, Yuexuan Zhu, Ming Xie, Yao Yu, Qishen Yang, Jun Zheng, Lin Yang, Qi Sun, Leqian Li, Xinhang Shi, Yongyuan Xiao, Hai Huang, Bisheng Cheng, Peng Wu   +16 more
wiley   +1 more source

Beyond the glitter: gold nanoparticles as powerful weapons against multi-drug resistant pathogens. [PDF]

Front Mol Biosci
Khalifa HO, Alkhoori H.
europepmc   +1 more source

Covalent Organic Frameworks‐Delivered Reuterin Drives Trained Immunity in Tumor‐Associated Macrophages to Enhance Melanoma Immunotherapy via Glycerophospholipid Metabolism

Advanced Science, EarlyView.
Covalent organic framework (COF)‐reuterin induces trained immunity in tumor‐associated macrophages, promoting the generation of nitric oxide and reactive oxygen species, thereby enhancing the antitumor immune response. Additionally, COF‐Reuterin directly kills tumor cells while simultaneously eradicating pathogenic intratumoural bacteria.
Jian‐Gang Zhang, Xiao‐Mei Zhang, Xi Wu, Cheng‐Kai Zhou, Zhen‐Zhen Liu, Xue‐Yue Luo, Liang Zhang, Wei Chen, Yong‐Jun Yang   +8 more
wiley   +1 more source

Microbial prevalence and understanding of their antimicrobial susceptibility in urinary tract of patients attending at shar teaching hospital (2018-2022). [PDF]

BMC Res Notes
Mohammed OA, Abubakr KT, Yaghoobi A, Khdhir HH, Ali DH, Abdalrahman PK, Ali BM, Hamarashid SH.   +7 more
europepmc   +1 more source

CXCR1 Depletion in Ly6C+ cDC2 Alleviates Acute Lung Injury via Modulation of Th17/Treg Balance

Advanced Science, EarlyView.
Pro‐inflammatory Ly6C⁺ cDC2s are identified as key effector cells mediating Cxcr1 signaling, driving the progression of ALI. Ly6C⁺ cDC2s release high levels of Il‐6 and Il‐1β, inducing Th17 differentiation. Cxcr1 deficiency reduces Il‐6 and Il‐1β production from Ly6C⁺ cDC2s through suppressing MEK1/ERK /NF‐κB signaling, thereby shifts naïve T cells ...
Shenghui Li, Wei Zhuang, Yang Wang, Hao Qin, Xichun Qin, Xianliang Yan, Xuefei Hu, Xiucheng Liu, Chang Chen   +8 more
wiley   +1 more source

Topographical Patterning of Cell‐Repellent Interfaces for Immune‐Stealth Implantable Electronics via Multiphoton Ablation Lithography

Advanced Science, EarlyView.
Immune‐stealth implantable electronics are developed using cell‐repellent interfaces created by multiphoton ablation lithography, which is the first research applying topographical cues on electronic devices. Laser‐patterned micro‐grooves and nano‐islands on ultrathin films can reduce immune cell adhesion to as low as 5%.
Hyunseon Seo, Gwan‐Jin Ko, Sangmin Song, Joong Hoon Lee, Youngmin Seo, Sungkeun Han, Chan‐Hwi Eom, Hyewon Kim, Seongsoo Kim, Kang‐Sik Lee, Yu‐Chan Kim, Hojun Kim, Si‐Eun Moon, Kyungwoo Lee, Seung Hwan Ko, Suk‐Won Hwang, Hojeong Jeon   +16 more
wiley   +1 more source

Why are there so few pathogens? Ecology and evolution in pathogen emergence. [PDF]

PLoS Biol
Drake JM.
europepmc   +1 more source