Results 161 to 170 of about 361,408 (311)

Microbiotoxicity: an under-recognised player in drug efficacy, toxicity, and health outcomes. [PDF]

NPJ Antimicrob Resist
Do Nascimento S, Theodosiou AA, Sergaki C.   +2 more
europepmc   +1 more source

Dipiperazine‐Phenyl Derivatives Based on Convergent Molecular Platforms Can Reverse Multidrug Resistance in Gram‐Negative Bacteria by Inhibiting Efflux and Permeabilizing Cell Membranes

Advanced Science, EarlyView.
By integrating a convergent molecular platform strategy, this study designed a novel dual‐target C5 to combat multidrug‐resistant Gram‐negative bacteria. C5 synergistically enhances antibiotic efficacy by inhibiting efflux pumps and increasing bacterial membrane permeability.
Jiale Dong, Ting Guo, Yi Huang, Yangchun Ma, Weijin Chen, Jie Xue, Jun Jiang, Enhui Dong, Yue Kong, Hang Ding, Wenlong Zhang, Shutao Ma   +11 more
wiley   +1 more source

Antibiotic Resistance Crisis: From Bacterial Bioprospecting to Artificial Intelligence. [PDF]

Environ Microbiol Rep
Cunha-Ferreira IC, Vizzotto CS, Peixoto J, Krüger RH.   +3 more
europepmc   +1 more source

Identification and Characterization of an In Silico Designed Membrane‐Active Peptide with Antiviral Properties

Advanced Science, EarlyView.
An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz, Niek van Hilten, Tatjana Weil, Thunchanok Thummaraj, Jeroen Methorst, Dennis Aschmann, Alexander Kros, Clarissa Read, Jasmina Gačanin, Herre Jelger Risselada, Jan Münch   +10 more
wiley   +1 more source

Editorial: Bacterial population heterogeneity, stress response and antibiotic tolerance. [PDF]

Front Cell Infect Microbiol
Subramanian A, Kurthkoti K, Mattioni Marchetti V, Vijay S.   +3 more
europepmc   +1 more source

Marine Biotechnology: A New Vision and Strategy for Europe [PDF]

Marine Board-ESF The Marine Board provides a pan-European platform for its member organisations to develop common priorities, to advance marine research, and to bridge the gap between science and policy in order to meet future marine science challenges ...
Boyen, C., Børresen, T., Dobson, A., Höfle, M., Ianora, A., Jaspars, M., Kijjoa, A., Olafsen, J., Querellou, J., Rigos, G., Wijffels, R.H.   +10 more
core   +2 more sources

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source

Microbial interactions in facilitating antibiotic activity and resistance evolution. [PDF]

Appl Environ Microbiol
Zhang L, Li S, Liu Z, Zhang R-r, Yang T, Liu D, Ding T, Lu X, Feng J.   +8 more
europepmc   +1 more source

A Natural Sweetener‐inducible Genetic Switch Controls Therapeutic Protein Expression in Mammals

Advanced Science, EarlyView.
This study develops a natural sweetener, the psicose‐inducible transgene expression (PURE) system based on an Agrobacterium tumefaciens–derived transcriptional repressor PsiR. The PURE system is highly specific to psicose, being insensitive to other sugars and structurally similar molecules.
Longliang Qiao, Zhihao Wang, Shasha Tang, Yuan Fang, Guiling Yu, Xiaoting Qiu, Lingxue Niu, Tao Yan, Xingwan Liu, Xiaoding Ma, Deqiang Kong, Yang Zhou, Ningzi Guan, Jinzhong Tian, Meiyan Wang, Haifeng Ye, Fengfeng Cai   +16 more
wiley   +1 more source

NSPOMdb: a curated dataset of the objectionable microorganisms of non-sterile products. [PDF]

Sci Data
Shen Y, Song M, Liu Y, Zhu W, Tai C, Shao H, Yang M, Fan Y, Ou HY.   +8 more
europepmc   +1 more source