Results 211 to 220 of about 330,368 (263)
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Biocides, drug resistance and microbial evolution
Current Opinion in Microbiology, 2001Antimicrobial biocides are widely used in critical human health situations in which rigorous infection control is needed. Increasingly, biocidal agents are being marketed for home use, although there is little evidence that they significantly improve home hygiene. Biocide resistance mechanisms share many themes with antibiotic resistance mechanisms.
David G. White, Patrick F. McDermott
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Microbial resistance to drug therapy: A review
American Journal of Infection Control, 1997Microbial resistance to the antimicrobials in standard use is becoming more prevalent. A historical perspective frames further discussion. Bacterial resistance is most common, but resistance has been identified in fungi, viruses, and parasites. Resistance is a complex phenomenon that involves the microorganism, the environment, and the patient ...
Felissa L. Cohen, Donna Tartasky
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1955
Publisher Summary It is unfeasible and unnecessary to coerce the complex biological events contributing to the origin of resistance into a single theory. Experimental evidence suggests that a few models define most examples of resistance development, particularly if the models are so combined as to provide either genotypic or phenotypic alterations ...
Vernon Bryson, Waclaw Szybalski
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Publisher Summary It is unfeasible and unnecessary to coerce the complex biological events contributing to the origin of resistance into a single theory. Experimental evidence suggests that a few models define most examples of resistance development, particularly if the models are so combined as to provide either genotypic or phenotypic alterations ...
Vernon Bryson, Waclaw Szybalski
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Quorum sensing and microbial drug resistance.
Yi chuan = Hereditas, 2016Microbial drug resistance has become a serious problem of global concern, and the evolution and regulatory mechanisms of microbial drug resistance has become a hotspot of research in recent years. Recent studies showed that certain microbial resistance mechanisms are regulated by quorum sensing system.
Lian-Hui Zhang +5 more
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The Design of New Drugs That Resist Microbial Inactivation
Clinical Infectious Diseases, 1979Several possible strategems for overcoming the development of bacterial resistance are discussed. The design of new drugs that resist microbial inactivation is reviewed, with particular emphasis on the aminoglycoside and beta-lactam antibiotics. Examples of alteration of the inactivation site, decreased enzyme affinity, steric hindrance of enzymic ...
L. D. Cama +2 more
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1989
Most often when the subject of antimicrobial resistance is discussed, the organizational emphasis is on individual antimicrobial agents or groups of agents. Thus we tend to see discussion of resistance to f3-lactams, tetracyclines, amino glycosides etc.
L. E. Bryan, A. Böck
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Most often when the subject of antimicrobial resistance is discussed, the organizational emphasis is on individual antimicrobial agents or groups of agents. Thus we tend to see discussion of resistance to f3-lactams, tetracyclines, amino glycosides etc.
L. E. Bryan, A. Böck
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Exploring Microbial Nanotoxicity Against Drug Resistance in Bacteria
2021The growing threat of antimicrobial resistance on human health urgently calls for the need to look for novel solutions to mitigate the grave effect of this global problem and save thousands of lives each year. Nanotechnology is an emerging area that is expected to be able to have solutions toward containing the rise and spread of multidrug-resistant ...
Rajeshwari Sinha +2 more
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Microbial Development of Drug Resistance: Mechanisms and Clinical Significance
CRC Critical Reviews in Clinical Laboratory Sciences, 1975Bacteria have demonstrated a disconcerting ability to develop resistance to antimicrobial agents nearly as quickly as new compounds become available. During the past two decades the molecular bases of several types of resistance have been elucidated.
Ruth M. Lawrence +2 more
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Microbial Pathogenesis and Antimicrobial Drug Resistance
2020Antimicrobial drug resistance has become a serious threat and it caused the death of 700,000 individuals in 2016. Gram-negative bacteria such as Acinetobacter, Pseudomonas, Enterobacter spp. Enterococcus faecium, Staphylococcus aureus, and Klebsiella pneumoniae are insensitive to antibiotics. E. faecium, S. aureus, K.
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Repositioning of non-antibiotic drugs as an alternative to microbial resistance: a systematic review
International Journal of Antimicrobial Agents, 2021The global spread of microbial resistance coupled with high costs and slow pace in the discovery of a new antibiotic have made drug repositioning an attractive and promising alternative in the treatment of infections caused by multidrug resistant (MDR) microorganisms. The reuse involves the production of compounds with lower costs and development time,
Vitória S. Foletto +4 more
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