Results 211 to 220 of about 4,768,335 (261)

Gut microbiota-driven immunomodulation in tuberculosis: targeting dysbiosis to overcome drug resistance. [PDF]

Front Immunol
Nie Q, Hu X, Zhang Y, Pan L, Zhang X, Zhou Y, Fu T, Zheng L, Xiao F, Liu Y, Du S, Liu J, Liu L, Xiong X, Wu Y, Fan D, Tao L, Ren F.   +17 more
europepmc   +1 more source

Sustainable Hydrogel‐Forming Microneedle‐Reservoir Patches for Transdermal Delivery of Hydrophilic Macromolecules: Biopolymers, Green Manufacturing and Translation

Advanced Science, EarlyView.
Hydrogel‐forming microneedle (HFMN)‐reservoir patches provide a modular route for controlled transdermal delivery of hydrophilic biomacromolecules. The platform integrates skin‐barrier penetration, sustainable biopolymers, scalable green manufacturing, hydration‐driven transport, model‐cargo validation, and translational quality requirements.
Siddharth Mohanty, Mehmet Onur Aydogdu, Sijia Kang, Xinbo Li, Mohan Edirisinghe   +4 more
wiley   +1 more source

Beyond antibiotics: artificial intelligence-enabled anti-infective ecosystems for next-generation precision therapeutics against antimicrobial resistance. [PDF]

Front Cell Infect Microbiol
Pattapulavar V, Ramanujam S, Badmanathan R, Christopher JG.   +3 more
europepmc   +1 more source

Dual‐Dynamically Crosslinked Nanogels Enable Prolonged Ocular Retention for Multimodal Dry Eye Therapy

Advanced Science, EarlyView.
This berberine‐loaded dual‐dynamically crosslinked nanogel integrates tannic acid‐zinc metal‐phenolic networks and carboxymethyl chitosan/aldehyde‐functionalized poly(ethylene glycol) dynamic Schiff base networks, achieving 1‐year colloidal and antioxidant stability, sustained corneal berberine exposure for 24 h to support convenient once‐daily dosing,
Yanru Xin, Sisi Chen, Shengli Huang, Mengqi Huang, Jingyan Zhu, Zijian Wang, Jianliang Shen, Qinxiang Zheng   +7 more
wiley   +1 more source

Beyond the Barrier: Overcoming Ocular Antimicrobial Resistance Through AI and Novel Therapeutics. [PDF]

Int J Mol Sci
Vasudevan A, Sivanantham A, Seema Sreekumar AB, Dayita MJ, Logeshwaran N, Sindhu Suresh S, Padmakumar S, Madhavan A, Babu P, Nair BG, Kumar GB.   +10 more
europepmc   +1 more source

Aged ZnO Nanoparticles Promote Breast Cancer Lung Metastasis by Remodeling the Pulmonary Microenvironment Through the CXCL10/Wnt/β‐Catenin Axis

Advanced Science, EarlyView.
In summary, pulmonary exposure to ZnO NPs, particularly aged NPs, promotes breast cancer metastasis by remodelling the lung tumour microenvironment. Aged ZnO NPs enrich M2‐macrophages, MDSCs and activated CAFs to form an immunosuppressive metastatic niche. CXCL10 from these cells drives metastasis via Wnt/β‐catenin activation.
Yong Zhu, Siyu Wang, Tong Lin, Jingyi Zhang, Jingya Yang, Dixiang Kang, Wenting Zhao, Na Yu, Meimei Wang   +8 more
wiley   +1 more source

High-fat diet induces an adaptive dysbiosis in the gut microbiota, associated with oxidative stress and the gut resistome profile in a rat model. [PDF]

Front Microbiol
Figueroa-Ajraz F, Bongcam-Rudloff E, González-Pizarro K, Dinamarca MA, Osses-Lobos L, Sotomayor-Zárate R, Ibacache-Quiroga C.   +6 more
europepmc   +1 more source