Results 241 to 250 of about 4,488,232 (311)

Helicobacter pylori‐Induced Persistent IGF2BP1 Activation Promotes Ferroptosis Resistance in Gastric Tumorigenesis

Advanced Science, EarlyView.
Helicobacter pylori infection induces sustained upregulation of the RNA‐binding protein IGF2BP1 in gastric epithelial cells, establishing a persistent epitranscriptomic program. IGF2BP1 stabilizes SLC7A11 mRNA in an m6A‐dependent manner to suppress ferroptosis and promote epithelial survival under oxidative stress. Pharmacological inhibition of IGF2BP1
Jing Ning, Xin Guan, Xinyu Hao, Jing Zhang, Deyao Li, Ying Xiong, Wenlin Zhang, Xiurui Han, Yanfei Lang, Meiling Zhou, Mengjie Yang, Zhi Huang, Tinghui Qu, Ming Zu, Qiao Meng, Weiwei Fu, Fengmin Lu, Jing Zhang, Xiangmei Chen, Tong Liu, Shigang Ding   +20 more
wiley   +1 more source

Pathological Signal‐Responsive Nanoplatforms for Sepsis: Integrating Biomarker Sensing With Spatiotemporal Drug Delivery and Immunomodulation

Advanced Science, EarlyView.
Biomarker‐triggered nanoplatforms transform sepsis therapy by coupling pathological sensing with precision drug release. This review reveals how microenvironment‐responsive nanomedicines enable stage‐specific intervention, improve therapeutic efficacy, and minimize systemic toxicity, while highlighting emerging opportunities for AI‐assisted and ...
Yukun Liu, Kang Wang, Kwet Kyawl Yan, Zhikai Xu, Xuan Zhao, Xiangjun Bai, Zhanfei Li, Yuchang Wang   +7 more
wiley   +1 more source

Self-Resistance as a Functional Beacon: Target-Directed Microbial Genome Mining from Classical Discovery to Automated Pipelines. [PDF]

Microorganisms
Wu J, Qiao M, Ma Y, Liu J, Wei J, Zhang P.   +5 more
europepmc   +1 more source

Intratumoral microbiome: a key regulator and novel therapeutic target for chemoresistance in pancreatic cancer. [PDF]

Front Cell Infect Microbiol
Wang Y, Wu J.
europepmc   +1 more source

The spiral evolution of techniques for the laboratory diagnosis of microbial infections. [PDF]

Front Cell Infect Microbiol
Tang YW, Ismail N, García-Contreras R.
europepmc   +1 more source

Editorial: Tuberculosis transmission: a battle between the host and the pathogen. [PDF]

Front Microbiol
Kurthkoti K, Sharma V, Vijay S.
europepmc   +1 more source

Oral dysbiosis: methodological evolution, the mobile resistome and the future of machine learning in dentistry. [PDF]

J Oral Microbiol
Lynch J, Bradshaw D, Hawkins R, Howlin R, Pavitt S, Do T.   +5 more
europepmc   +1 more source

Four Decades of Cytochrome P450 Research in Africa: A Historical Overview of Scientific Contributions, Research Trends, and Future Directions. [PDF]

Biology (Basel)
Syed K.
europepmc   +1 more source