Nature CommunicationsNew solutions are needed to detect genotype-phenotype associations involved in microbial drug resistance. Herein, we describe a Group Association Model (GAM) that accurately identifies genetic variants linked to drug resistance and mitigates false ...
Julian G. Saliba +10 more
doaj +1 more source
Antimicrobial resistance and antibiotic consumption in Mexican hospitals
Salud Pública de México, 2019 Objective. To establish the current situation of antimicrobial resistance and antibiotic consumption in Mexican hospitals. Materials and methods. Antimicrobial susceptibility data from blood and urine isolates were collected.
María Guadalupe Miranda-Novales +7 more
doaj +1 more source
Predicting allostery and microbial drug resistance with molecular simulations
Current Opinion in Structural Biology, 2018 Beta-lactamase enzymes mediate the most common forms of gram-negative antibiotic resistance affecting clinical treatment. They also constitute an excellent model system for the difficult problem of understanding how allosteric mutations can augment catalytic activity of already-competent enzymes.
George A Cortina, Peter M Kasson
openaire +3 more sources
Characterization of extended-spectrum β-lactamases produced by Escherichia coli isolated from hospitalized and nonhospitalized patients : emergence of CTX-M-15-producing strains causing urinary tract infections [PDF]
, 2010 Extended-spectrum β-lactamase-producing Escherichia coli isolates were obtained from hospitalised and non-hospitalised patients in Belgium between August 2006 and November 2007.
Butaye, Patrick +10 more
core +1 more source
Epidermal Patch Technologies for Integrated Healthcare and Infection Management
Advanced Healthcare Materials, EarlyView.Epidermal patches have evolved from simple wound coverings into multifunctional, skin‐conformable platforms integrating drug delivery, biosensing, and therapeutic functionalities. This review highlights their material innovations, fabrication strategies, and intelligent designs, including hydrogels, microneedles, and flexible electronics, while ...
Yuqi Wang +7 more
wiley +1 more source
GCGACNN: A Graph Neural Network and Random Forest for Predicting Microbe–Drug Associations
BiomoleculesThe interaction between microbes and drugs encompasses the sourcing of pharmaceutical compounds, microbial drug degradation, the development of drug resistance genes, and the impact of microbial communities on host drug metabolism and immune modulation ...
Shujuan Su +3 more
doaj +1 more source
Integrating Vibrio natriegens for Photon Manipulation in Living Lighting Devices
Advanced Materials, EarlyView.Rationalization of genetic and material engineering tools has enabled the engineering of fluorescent Vibrio natriegens (V. natriegens) to fabricate straightforward, highly emissive and stable V. natriegens‐silicones color filters for the first red‐emitting bacteria‐hybrid light‐emitting diodes. This pinpoints V. natriegens as a high‐performance protein
Stephanie Willeit +6 more
wiley +1 more source
Фундаментальная и клиническая медицина, 2018 Aim. To determine microbial resistance to chlorhexidine. Materials and Methods. We performed a systematic review and analyzed the data from the regional monitoring of microbial resistance to chlorhexidine. Results.
DARYA V. Kvashnina, OLGA V. Kovalishena
doaj
The fecal resistome of dairy cattle is associated with diet during nursing. [PDF]
, 2019 Antimicrobial resistance is a global public health concern, and livestock play a significant role in selecting for resistance and maintaining such reservoirs.
DePeters, Edward J +7 more
core +1 more source
Does microbicide use in consumer products promote antimicrobial resistance? A critical review and recommendations for a cohesive approach to risk assessment [PDF]
, 2013 The increasing use of microbicides in consumer products is raising concerns related to enhanced microbicide resistance in bacteria and potential cross resistance to antibiotics.
Bloomfield, Sally +12 more
core +3 more sources