Results 251 to 260 of about 273,925 (284)

Laboratory detection of primary and acquired drug resistance in human lymphatic neoplasms.

Cancer treatment reports, 1986
We tested the ability of the differential staining cytotoxicity (DiSC) assay to discriminate between sensitive and resistant cell populations in human lymphatic neoplasms. First, the in vitro activity spectra of the most important drugs paralleled the known clinical activity spectra of the same agents. Second, there were highly significant correlations
L M, Weisenthal, P L, Dill, J Z, Finklestein, T E, Duarte, J A, Baker, E M, Moran   +5 more
openaire   +1 more source

INCB160058 selectively targets JAK2V617F-driven hematopoiesis in diverse and drug-resistant models of myeloproliferative neoplasms

Blood
Abstract INCB160058 is a first-in-class, orally bioavailable Janus kinase 2 (JAK2) V617F mutant-selective inhibitor, currently being studied in phase 1 clinical trials (eg, NCT06313593) in patients with myeloproliferative neoplasms (MPNs) harboring JAK2V617F mutation.
Hamza Celik, Gaurang Trivedi, Angelo Albertoni, Brittney Wass, Eddy Yue, Yanran Ai, Caroline Marty, Elodie Rosa, Maxime Evrard, William Vainchenker, Florence Pasquier, Cynthia Timmers, Sunkyu Kim, Ricardo Macarron, Isabelle Plo, Matthew Stubbs   +15 more
openaire   +1 more source

[Efficacy of surgical management combined with chemotherapy in the treatment of drug-resistant gestational trophoblastic neoplasm].

Zhonghua fu chan ke za zhi, 2011
To evaluate the efficacy of surgical management combined with chemotherapy in the treatment of drug-resistant gestational trophoblastic neoplasm (GTN) patients, and investigate factors influencing the outcome of the surgery combined with chemotherapy.Medical records of 42 patents with drug-resistant GTN who were treated by chemotherapy combined with ...
Feng-Zhi, Feng, Yang, Xiang, Yang, Cao, Lei, Li, Xi-Run, Wan, Xiu-Yu, Yang   +5 more
openaire   +1 more source

Perturbation of in vitro drug resistance in human lymphatic neoplasms by combinations of putative inhibitors of protein kinase C.

Cancer treatment reports, 1988
Fresh specimens of human lymphatic neoplasms were tested with the differential staining cytotoxicity assay. Cells from relapsed patients with acute lymphoblastic leukemia (ALL) were significantly more resistant to vincristine, dexamethasone, and doxorubicin in the assay than were cells from previously untreated patients.
L M, Weisenthal, Y Z, Su, T E, Duarte, P L, Dill, R A, Nagourney   +4 more
openaire   +1 more source

Engaging the Endocannabinoid System in Neuroendocrine Neoplasms (NENs) potentiates treatment outcomes and null drug resistance

Endocrine Abstracts, 2022
Polak Shani Avniel-, David Polak, Kira Oleinikov, David J Gross, Ori Wald, Uzi Izhar, Haggi Mazeh, Yotam Drier, Simona Glasberg   +8 more
openaire   +1 more source

Impacts of Pharmacists-Managed Oncology Outpatient Clinic on Resolving Drug-Related Problems in Ambulatory Neoplasm Patients: A Prospective Study in China

Inquiry (United States), 2021
Xincai Zhao, Yonggang Wang, Haiyan Hu
exaly  

Studies on drug resistance—II. Kinase patterns in P815 neoplasms sensitive and resistant to 1-β-d-arabinofuranosylcytosine

Biochemical Pharmacology, 1970
D, Drahovsky, W, Kreis
openaire   +2 more sources

Antibody–drug conjugates: Smart chemotherapy delivery across tumor histologies

Ca-A Cancer Journal for Clinicians, 2022
Paolo Tarantino, Roberto Carmagnani Pestana, Chiara Corti   +2 more
exaly  

SOME ASPECTS OF DRUG RESISTANCE IN NEOPLASMS

Annals of the New York Academy of Sciences, 1958
openaire   +2 more sources

Neoplasm Reports in Food and Drug Administration Adverse Event Reporting System Following Angiotensin Receptor Blocker Recalls

Circulation: Cardiovascular Quality and Outcomes, 2021
Robert Cohen Sedgh, Jungyeon Moon, Cynthia A Jackevicius   +2 more
exaly