Results 241 to 250 of about 286,157 (290)

Single-Cell Lineage Tracing Uncovers Resistance Signatures and Sensitizing Strategies to FLT3 Inhibitors in Acute Myeloid Leukemia. [PDF]

Cancer Res
Eriksson J, Zheng S, Popa M, Bao J, Dai J, Wang W, McCormack E, Vähärautio A, Tang J.   +8 more
europepmc   +1 more source

Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice

Advanced Healthcare Materials, EarlyView.
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec, Randy Lee, Jingming Cao, Sophie Marolleau, Julien Nicolas, Sébastien Benzekry   +5 more
wiley   +1 more source

Lipid Metabolism and Breast Cancer Therapy: An Integrative Literature Review. [PDF]

Breast Cancer (Dove Med Press)
Gong X, Zhang D, Wen Z, Zeng J, Tang Y, Deng J, Bin Y.   +6 more
europepmc   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

CDX2 confers ferroptosis resistance in stage II-III colon cancer via upregulation of NUPR1. [PDF]

Cell Death Dis
Yu J, Mu M, Zhao C, Li X, Ma X, Dong Z, Sun X, Zheng J.   +7 more
europepmc   +1 more source

Processing of mitochondrial precursor proteins [PDF]

, 1984
Neupert, Walter, Schmidt, Bernd
core  

Engineering Resatorvid‐Loaded Sub‐Microgels of Epigallocatechin‐3‐gallate/Hyaluronic Acid to Treat Acute Lung Injury

Advanced Healthcare Materials, EarlyView.
This study presents HAEP@Res sub‐microgels as a lung‐targeted delivery system integrating antioxidant activity with anti‐inflammatory therapy. The sub‐microgels demonstrate excellent biocompatibility, efficiently scavenge intracellular ROS, and downregulate pro‐inflammatory cytokines and genes in a Bleo‐induced ALI mouse model. These findings highlight
Bo Liu, Olawale Alimi Alimi, Benjamin Stearnes, Svetlana Romanova, Brady J. Sillman, Mena Asha Krishnan, Kristina Bailey, Benson J. Edagwa, Huanhuan Joyce Chen, Han‐jun Wang, Bin Duan   +10 more
wiley   +1 more source

Editorial: Altered metabolic traits in gastro-intestinal tract cancers, volume II. [PDF]

Front Endocrinol (Lausanne)
Parte S, Kumavath R, Pothuraju R, Sharma S, Bhatia R.   +4 more
europepmc   +1 more source

Fluid-Derived Organoids from Pleural Effusion and Ascites: Emerging Models for Drug Resistance and Personalized Oncology. [PDF]

J Cancer
Chen Y, Xu X, Chen J, Yin M, Chen J, Qi Z, Shi M, Su W.   +7 more
europepmc   +1 more source

Inhibition of BIRC5 and MCL-1 as a potential treatment strategy to overcome drug resistance in Mantle Cell Lymphoma. [PDF]

Blood Cancer J
Pfitzer J, Chakravarti S, Mazumder S, Li F, Mukherjee UK, Mitra AK.   +5 more
europepmc   +1 more source