Results 171 to 180 of about 1,232,228 (310)

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Drug-Resistance of Enteric Bacteria

, 1962
Mitsuo Kameda, Kenji Harada, Masaru Suzuki, S Mitsuhashi   +3 more
openalex   +4 more sources

The Role of Mesenchymal Stem Cells in Drug Resistance in Lung Neoplasms. [PDF]

J Cancer Prev
Kang D, Yeon E, Kim S, Han E, Kang T, Song H, Kim J.   +6 more
europepmc   +1 more source

Drug Resistance of Staphylococci [PDF]

, 1968
Tokuhiko Kasuga, Susumu Mitsuhashi
openalex   +1 more source

The rapidly growing landscape of RAS inhibitors: from selective allele blockade to broad inhibition strategies

Molecular Oncology, EarlyView.
RAS‐targeted therapies have become a clinical reality. Although promising results in patients have been achieved, there are still challenges ahead such as coping with drug resistance. Here we summarize selected RAS inhibitors targeting either individual KRAS mutant isoforms (KRASG12C, KRASG12D, KRASG12V) or exhibiting a wider inhibitory spectrum ...
Matthias Drosten, Mariano Barbacid
wiley   +1 more source

Diverse proviral structure of HIV integrants in clonally expanded cells

Journal of Virus Eradication, 2015
F.R. Simonetti, J. Spindler, X. Wu, F. Maldarelli, J.M. Coffin   +4 more
doaj   +1 more source

Cancer 3D Models: Essential Tools for Understanding and Overcoming Drug Resistance. [PDF]

Oncol Res
Jovanović Stojanov S, Grozdanić M, Ljujić M, Dragičević S, Dragoj M, Dinić J.   +5 more
europepmc   +1 more source

Trial of Bronchodilator Drugs Given by Metered Aerosol with a Comparison of Two Bedside Methods of Estimating Airway Resistance [PDF]

, 1966
B I Hoffbrand, M. I. Hoffbrand, Iain D. Hill, P J D Heaf   +3 more
openalex   +1 more source

A guide to reactive oxygen species in tumour hypoxia: measurement and therapeutic implications

Molecular Oncology, EarlyView.
Hypoxia reshapes tumour redox landscapes by altering compartmental ROS production (mitochondria, NOX, ER, peroxisomes). Accurate interpretation requires oxygen‐contextualised measurement (live biosensors, chemical probes, EPR, LC–MS) and awareness of artefacts (reoxygenation, probe specificity).
Lina Hacker, Elysia Sarsam, Stuart J. Conway, Ester M. Hammond   +3 more
wiley   +1 more source

Distribution of nontuberculous Mycobacteria among presumptive drug resistance tuberculosis patients from a ministry of health drug resistance surveillance program, in western Kenya. [PDF]

J Clin Tuberc Other Mycobact Dis
Albert O, Lazarus O, Benjamin OJ, Ben O, Ruth S, Joan T, Jeremiah O, Steve W, Ouma C.   +8 more
europepmc   +1 more source