Results 151 to 160 of about 1,288,674 (265)

Epigenetic modifications in cancer drug resistance: molecular mechanisms and therapeutic interventions. [PDF]

Mol Biomed
Yang J, Zhang M, Zhong Y, Sun C, Zhuang J.   +4 more
europepmc   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

The role of RAS mutations in leukemia progression, differentiation, and drug resistance. [PDF]

Leuk Res Rep
Jiang C, Wang H, Zhao J, Xu Y, Duan S.
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Hypoxia-Driven Mechanisms of Drug Resistance in Prostate Cancer. [PDF]

Cancers (Basel)
Ressel MR, Flores CE, Warfel NA.
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Diverse proviral structure of HIV integrants in clonally expanded cells

Journal of Virus Eradication, 2015
F.R. Simonetti, J. Spindler, X. Wu, F. Maldarelli, J.M. Coffin   +4 more
doaj   +1 more source

Liquid-Liquid Phase Separation in Cancer Drug Resistance: Mechanisms and Therapeutic Opportunities. [PDF]

Oncol Res
Zhao Y, Sun C, Dong Q, He J, Wang Y, Bi L.   +5 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

ALDH3A2-mediated fatty acid synthesis induces ferroptosis and AML drug resistance. [PDF]

iScience
Huang Y, Zhao Y, Yan P, Long Z, Xia C, Jiang L, Zhang Y, Cheng J, Liu F, Wu Q, Zhou Z, Jiang X.   +11 more
europepmc   +1 more source