Results 151 to 160 of about 4,670,790 (255)

HIV-1 Drug Resistance Mutations in Children: A Systematic Review of Global Genotypic Evidence (2014-2026). [PDF]

Pathogens
Jouf G, Alami AB, Maazaz N, Benchekroun S, Elharti E, Belbacha I, Ihazmad H, Jaoudi RE, Benhida R, Rchiad Z, Oumzil H.   +10 more
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Machine learning-based analysis of drug resistance mutations in Mycobacterium tuberculosis. [PDF]

PLoS One
Thankamani A, C L B, Doss C GP.
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Evolutionary diversity of the pfmdr1 hinge region and association with antimalarial drug resistance mutations post ACT introduction. [PDF]

Int J Parasitol Drugs Drug Resist
Hocke EF, Hansson H, Chopo-Pizarro A, Wellmann L, Kahunu GM, Mavoko HM, Nkoli PM, Sompwe EM, Mbongi D, Mitashi P, Ali IM, Nji A, Mbacham W, Moussiliou A, Dandonougbo C, Kpemasse A, Affoukou C, Akogbeto M, Ngufor C, Beshir K, Mousa A, Roper C, Sutherland CJ, Alifrangis M.   +23 more
europepmc   +1 more source

Genome-wide analyses of Mycobacterium tuberculosis complex isolates reveal insights into circulating lineages and drug resistance mutations in The Gambia. [PDF]

Sci Rep
Faal F, Top N, Jobe O, Colley SM, Ayorinde A, Mendy A, Sarr-Kuyateh B, Donkor S, Antonio M, de Jong BC, Rachow A, Kampmann B, Sutherland JS, Li H, Blundell TL, Campino S, Kohl T, Dreyer V, Neimann S, Pandurangan AP, Clark TG, Phelan JE, Tientcheu LD.   +22 more
europepmc   +2 more sources

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Analysis of HIV Drug Resistance Mutations Along With Treatment Outcomes of Efavirenz-Based Regimens in Patients With V179D/E Mutations in Guangzhou, China. [PDF]

Can J Infect Dis Med Microbiol
Zheng X, Xiao Y, Zhang Y, Wang P, Zhang Y, Li L, Zheng Y, Li X, Chen D, Yang X, Huang Z.   +10 more
europepmc   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

HIV-1 Genetic Diversity and Drug Resistance Mutations Among Patients on Antiretroviral Therapy in Nairobi County, Kenya. [PDF]

Adv Virol
Angiro E, Ngayo M, Wahome C, Mungiria J, Nyamache A.   +4 more
europepmc   +1 more source