Results 291 to 300 of about 8,234,457 (404)

Durable Physically Mixed Microporous and Mesoporous MOFs/Nanofiber Aerogel 3D Composites for Effective Toxic Gas Capture and Organophosphonate Detoxification

Advanced Functional Materials, EarlyView.
Ultralight 3D nanofibrous aerogels embedded with metal‐organic frameworks effectively capture and neutralize toxic gases and organophosphonates. Incorporating mesoporous UiO‐66‐NH2 and HKUST‐1 into PAN/PVP fibers enables high MOF loading while maintaining mechanical strength and structural stability.
Mai O. Abdelmigeed, Muhammed Ziauddin Ahmad Ebrahim, John J. Mahle, Brandon B. Blount, Gregory W. Peterson, Saad A. Khan, Gregory N. Parsons   +6 more
wiley   +1 more source

A population-based cohort to evaluate drug safety during pregnancy (PREGVAL): rationale, design, and baseline characteristics. [PDF]

Eur J Epidemiol
Sánchez-Sáez F, Sanfélix-Gimeno G, Hurtado I, García-Sempere A, Garcés-Sánchez M, Llopis-Cardona F, Peiró S, Rodríguez-Bernal CL.   +7 more
europepmc   +1 more source

Additional file 2 of Protocol for a phase 2, partially blinded, randomized trial assessing the safety and efficacy of sorfequiline or bedaquiline in combination with pretomanid and linezolid in adult participants with newly diagnosed, drug-sensitive, smear-positive pulmonary tuberculosis (NC-009)

M. Olugbosi, M. Beumont, L. Lombard, Jerry Nedelman, J. Timm, T. Black, Rebecca S. Bruning-Barry, Dean Hickman, Antonio Lombardi, M. Betteridge, Erica Egizi, Lisa Marcopulos, J. Henderson, Stephanie Seidel, Salah Foraida, Majda Benhayoun, E. Sun   +16 more
openalex   +1 more source

Safety Profile, Toxicokinetic, and Intestinal Absorption Differences of a Naturally-Derived Anti-Rheumatic Drug, Sinomenine Hydrochloride, in Normal and Arthritic Rats [PDF]

Yini He, Hong Huang, Gejing Li, Ye Zhang, Junjie He, Lin Ye, Feichi Wu, Jianye Yan, Xiong Cai, Liang Liu   +9 more
openalex   +1 more source

Programmable DNA‐Peptide Hybrid Nanostructures for Potent Neutralization of Multiple Influenza a Virus Subtypes

Advanced Functional Materials, EarlyView.
A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao, Abhisek Dwivedy, Payton L. Haak, Dhanush Gandavadi, Laurie A. Rund, Chi Chen, Vineetha Mareddy, Lifeng Zhou, Jinwei Duan, Ying Fang, Andrew J. Steelman, Xing Wang   +11 more
wiley   +1 more source

High-Frequency, At-Home Monitoring of Drug Safety and Tolerability in Clinical Trials: Results From Studies of Fluvoxamine for COVID-19 Treatment. [PDF]

Clin Transl Sci
Lenze EJ, Nykamp M, Miller JP, Stevens A, Schweiger J, Gettinger T, Yingling M, Zhang Y, Nicol GE, Zorumski CF, Reiersen AM.   +10 more
europepmc   +1 more source

Qualitative insights into drug use safety strategies and social support among sexual minority women who inject drugs in Baltimore, Maryland [PDF]

Jennifer L. Glick, Leanne Zhang, Aimee K. Huang, Megan L. Nguyen, Danielle German   +4 more
openalex   +1 more source

Upconversion Nanoparticles Embedded Photonic Contact Lens for Transepithelial Corneal Crosslinking Using Hyaluronate – Riboflavin Conjugate

Advanced Functional Materials, EarlyView.
A minimally invasive, transepithelial corneal cross‐linking (TE‐CXL) approach is presented using upconversion nanoparticles (UCNPs)‐loaded contact lenses (UCLs), after topical delivery of hyaluronate–riboflavin conjugates. The NIR‐to‐UV/blue light conversion by UCNPs in a UCL can activate riboflavin for TE‐CXL, resulting in the biomechanical strength ...
Gibum Lee, Inhoo Choi, Anara Molkenova, Yengwoo Son, Seungmin Yang, Mina Kwon, Tae‐Im Kim, Ki Su Kim, Sei Kwang Hahn   +8 more
wiley   +1 more source

A refined set of RxNorm drug names for enhancing unstructured data analysis in drug safety surveillance. [PDF]

Exp Biol Med (Maywood)
Guo W, Dong F, Liu J, Aslam A, Patterson TA, Hong H.   +5 more
europepmc   +1 more source

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

Advanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo, Nguyen Thi Nguyen, LiLi Guo, Ngoc Man Phan, Hyunsu Shin, Tae‐il Kim, Yu Seok Youn, Jaeyun Kim   +7 more
wiley   +1 more source