Results 251 to 260 of about 112,008 (305)

Hypofractionated Radiotherapy Induces ISG15+MHC‐I+ Neutrophils to Augment Anti‐Tumor Immunity and Prime Immune Checkpoint Blockade Responses in Rectal Cancer

Advanced Science, EarlyView.
ABSTRACT Our previous clinical trials had demonstrated that neoadjuvant hypofractionated radiotherapy (HFRT) combined with immunotherapy yields promising clinical outcomes in locally advanced rectal cancer (LARC). However, this combined modality benefits only a subset of patients, highlighting the need to uncover the mechanisms underlying how ...
Lichao Liu, Haihong Wang, Mingjie Li, Qian Xu, Linlin Zheng, Chaoqun Han, Zhenwei Zou, Jinghua Ren, Xiaorong Dong, Peng Zhang, Kaixiong Tao, Zhenyu Lin, Tao Zhang   +12 more
wiley   +1 more source

3D Cardiac Constructs in Drug Discovery: Current Advances and Future Challenges. [PDF]

Research (Wash D C)
Liu C, Guo J, Mirzayeva G, Spanos M, Teng R, Li G, Cretoiu D, Chen Z, Xiao J.   +8 more
europepmc   +1 more source

RHOJ derived peptide promotes chemosensitivity by inhibiting glutamine metabolism in gastric cancer. [PDF]

J Transl Med
Li J, Li H, Ye F, Wang J, Li F, Bei S, Zhang X, Jiang J, Feng L.   +8 more
europepmc   +1 more source

ONX-0914 Suppresses Hormone-Sensitive Prostate Cancer by Promoting O-GlcNAcylation-Mediated Stabilization of TCF7L1. [PDF]

Oncol Res
Xian P, Feng Z, Yu H, Yin H, Chen H, Shi T, Li X, Zhang C, Bai X, Gou X, Li X, Li J.   +11 more
europepmc   +1 more source

New potentials in biomedical application of hydrated electrons: A functional and biomedical effects study of an electromagnetic base liquid containing hydrated electrons. [PDF]

PLoS One
Zheng Z, Ran F, Liang L, Zhang Y, Li X, Zhang L, Bi L.   +6 more
europepmc   +1 more source

An LNA gapmer antisense oligonucleotide inhibitor of human NNMT. [PDF]

Mol Ther Nucleic Acids
Chen S, Poudel BH, Veedu RN.
europepmc   +1 more source

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Tumor-specific GPX4 degradation enhances ferroptosis-initiated antitumor immune response in mouse models of pancreatic cancer

Science Translational Medicine, 2023
Lipid peroxidation–dependent ferroptosis has become an emerging strategy for tumor therapy. However, current strategies not only selectively induce ferroptosis in malignant cells but also trigger ferroptosis in immune cells simultaneously, which can ...
Jingbo Li, Jiao Liu, Zhuan Zhou, Runliu Wu, Xin Chen, Chunhua Yu, Brent R. Stockwell, Guido Kroemer, Rui Kang, D. Tang   +9 more
semanticscholar   +1 more source