Recent advances in surface decoration of nanoparticles in drug delivery
Frontiers in NanotechnologyNanoparticulate delivery systems have been attracting attention in pharmaceutical sciences for enhanced drug bioavailability and targeted delivery. Specifically, these systems can enhance the solubility of poorly water-soluble drugs, protect therapeutic ...
Phuong-Dung Ly +5 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Didactic Strategy for Students to Prepare a Protocol to Conduct a Drug Stability Study [PDF]
, 2019 José Ml. Fallas-Ramírez +1 more
openalex +1 more source
Inclusion of Montelukast in y-Cyclodextrin: Presenting a Mechanochemical Route to Improve Drug Stability and Solubility [PDF]
, 2020 Jéssica S. Barbosa +3 more
openalex +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
A validation of mobile sensing actigraphy devices for generating a biomechanical model of posture [PDF]
, 2017 Mobile sensing actigraphy was tested and validated as a modality for computing dynamic posturography. Twelve healthy volunteer subjects (6 male) were administered risperidone and assessed for postural stability using a NeuroCom® Balance Master system and
Detheridge, Craig Neal
core +1 more source
Prediction of Drug Stability Using Deep Learning Approach: Case Study of Esomeprazole 40 mg Freeze-Dried Powder for Solution. [PDF]
Pharmaceutics, 2021 Ajdarić J +4 more
europepmc +1 more source
Structure Guided Drug Designing Coupled to Advanced Molecular Dynamics Revealed Differential Binding Properties (Affinity/Stability) of Celecoxib and Niflumic Acid in the Active Site of Cyclooxygenase-2 Enzyme [PDF]
, 2022 Shabir Ahmad Ganai +4 more
openalex +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Formulation of gliclazide using self-nano-emulsification technology [PDF]
, 2018 Self-nano-emulsifying drugs delivery systems present an effective drug delivery system for the formulation of a hydrophobic drug with poor water-solubility.
Abdel-Aziz, Farah +4 more
core